SCHEMBL19929010

SCHEMBL19929010

O=P(c1ccccc1)(c1ccccc1)c1ccc(-c2ccc3nc4c5ccccc5c5ccccc5n4c3c2)nc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.38
HPGD P15428 5/20 0.38
KDM4E B2RXH2 5/20 0.38
KMT2A Q03164 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
MAPT P10636 2/20 0.34
POLB P06746 2/20 0.34
HSD17B10 Q99714 2/20 0.34
LMNA P02545 1/20 0.34
TP53 P04637 1/20 0.34
MEN1 O00255 1/20 0.32
TOP1 P11387 1/20 0.31
TUBB4A P04350 1/20 0.31
TUBB P07437 1/20 0.31
TUBA3C P0DPH7 1/20 0.31
TUBA1B P68363 1/20 0.31
TUBA4A P68366 1/20 0.31
TUBB4B P68371 1/20 0.31
TUBB3 Q13509 1/20 0.31
TUBB2A Q13885 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18999402 0.96 ALDH1A1 (0.38) ALDH1A1HPGDKDM4EKMT2ASMN1; SMN2
SCHEMBL19960011 0.95 ALDH1A1 (0.35) ALDH1A1HPGDKDM4EKMT2ASMN1; SMN2
SCHEMBL19929009 0.93 HPGD (0.43) ALDH1A1HPGDKDM4EKMT2ASMN1; SMN2
SCHEMBL19929007 0.92 HPGD (0.39) ALDH1A1HPGDKDM4EKMT2ASMN1; SMN2
SCHEMBL19960510 0.91 ALDH1A1 (0.33) ALDH1A1HPGDKDM4EKMT2ASMN1; SMN2
SCHEMBL19929041 0.91 KDM4E (0.40) ALDH1A1HPGDKDM4EKMT2ASMN1; SMN2
SCHEMBL19929001 0.91 KDM4E (0.40) ALDH1A1HPGDKDM4EKMT2ASMN1; SMN2
SCHEMBL19960023 0.90 ALDH1A1 (0.33) ALDH1A1HPGDKDM4EKMT2ASMN1; SMN2
SCHEMBL20276037 0.89 ALDH1A1 (0.45) ALDH1A1HPGDKDM4EKMT2ASMN1; SMN2
SCHEMBL19928981 0.89 ALDH1A1 (0.45) ALDH1A1HPGDKDM4EKMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10547008-B2 Organic light emitting device LG CHEM, LTD. (KR) 2020-01-28 US disclosed
US-20180069180-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2018-03-08 US disclosed
US-20180069180-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM, LTD. (KR) 2018-03-08 US disclosed