Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 3/20 | 0.62 |
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.62 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.57 |
| ▸ | POLA1 | P09884 | 1/20 | 0.57 |
| ▸ | POLG | P54098 | 1/20 | 0.57 |
| ▸ | FAP | Q12884 | 1/20 | 0.57 |
| ▸ | NSD3 | Q9BZ95 | 7/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.53 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.50 |
| ▸ | NSD2 | O96028 | 6/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.48 |
| ▸ | CA2 | P00918 | 1/20 | 0.48 |
| ▸ | CA4 | P22748 | 1/20 | 0.48 |
| ▸ | CA9 | Q16790 | 1/20 | 0.48 |
| ▸ | PI4KA | P42356 | 1/20 | 0.46 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.46 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.46 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15532108 | 0.94 | FGFR1 (0.67) | FGFR1SLC22A6ABCB11POLA1POLG | |
| SCHEMBL28797052 | 0.88 | FGFR1 (0.74) | FGFR1SLC22A6ABCB11POLA1POLG | |
| SCHEMBL19929316 | 0.87 | SLC22A6 (0.45) | FGFR1SLC22A6ABCB11POLA1POLG | |
| SCHEMBL16063256 | 0.86 | FGFR1 (0.60) | FGFR1SLC22A6ABCB11POLA1POLG | |
| SCHEMBL23677944 | 0.86 | FGFR1 (0.64) | FGFR1SLC22A6ABCB11POLA1POLG | |
| SCHEMBL18755568 | 0.86 | FGFR1 (0.71) | FGFR1SLC22A6ABCB11POLA1POLG | |
| SCHEMBL19470259 | 0.84 | FGFR1 (0.71) | FGFR1SLC22A6ABCB11POLA1POLG | |
| SCHEMBL19470492 | 0.84 | FGFR1 (0.66) | FGFR1SLC22A6ABCB11POLA1POLG | |
| SCHEMBL19508638 | 0.82 | CYP3A4 (0.65) | FAP | |
| SCHEMBL17613076 | 0.82 | SLC22A6 (0.59) | FGFR1SLC22A6ABCB11POLA1POLG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180064737-A1 | ACYCLIC NUCLEOSIDE PHOSPHONATE DIESTERS | UNIV CALIFORNIA (US) | 2018-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180064737-A1 | ACYCLIC NUCLEOSIDE PHOSPHONATE DIESTERS | NTPCR, PNP, TYMP | FGFR1 3394/4885SLC22A6 1764/4885ABCB11 2382/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.