Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A6 | Q4U2R8 | 2/20 | 0.45 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.45 |
| ▸ | CDK1 | P06493 | 1/20 | 0.44 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.44 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | POLA1 | P09884 | 2/20 | 0.43 |
| ▸ | POLG | P54098 | 2/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | FAP | Q12884 | 1/20 | 0.43 |
| ▸ | SERPINA3 | P01011 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 4/20 | 0.42 |
| ▸ | TMIGD3 | P0DMS9 | 2/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.39 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19929313 | 0.87 | FGFR1 (0.62) | SLC22A6FGFR1POLA1POLGABCB11 | |
| SCHEMBL2734845 | 0.86 | POLB (0.52) | SLC22A6FGFR1CDK1CCNB1CCNE1 | |
| SCHEMBL17622587 | 0.84 | POLB (0.60) | POLA1POLGPOLB | |
| SCHEMBL15532108 | 0.81 | FGFR1 (0.67) | SLC22A6FGFR1POLA1POLGABCB11 | |
| SCHEMBL8400651 | 0.80 | CDK1 (0.53) | SLC22A6FGFR1CDK1CCNB1CCNE1 | |
| SCHEMBL23394748 | 0.79 | POLB (0.49) | SLC22A6FGFR1POLA1POLGABCB11 | |
| SCHEMBL8400650 | 0.79 | CDK1 (0.51) | SLC22A6FGFR1CDK1CCNB1CCNE1 | |
| SCHEMBL2734810 | 0.78 | FGFR1 (0.59) | SLC22A6FGFR1CDK1CCNB1CCNE1 | |
| Pmedap SCHEMBL29571667 | 0.78 | FGFR1 (0.72) | SLC22A6FGFR1CDK1CCNB1CCNE1 | |
| Pmedap SCHEMBL215611 | 0.78 | FGFR1 (0.72) | SLC22A6FGFR1CDK1CCNB1CCNE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180064737-A1 | ACYCLIC NUCLEOSIDE PHOSPHONATE DIESTERS | UNIV CALIFORNIA (US) | 2018-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180064737-A1 | ACYCLIC NUCLEOSIDE PHOSPHONATE DIESTERS | NTPCR, PNP, TYMP | SLC22A6 1764/4885FGFR1 3394/4885CDK1 948/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.