Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | KAT2A | Q92830 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | PRKCA | P17252 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | LGALS8 | O00214 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | POLA1 | P09884 | 1/20 | 0.30 |
| ▸ | CA12 | O43570 | 1/20 | 0.30 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1376392 | 0.90 | HSD17B10 (0.47) | HSD17B10CYP3A4MAPTCYP2C9CYP2C19 | |
| SCHEMBL11687845 | 0.87 | HSD17B10 (0.52) | HSD17B10CYP3A4MAPTCYP2C9CYP2C19 | |
| SCHEMBL10735423 | 0.85 | POLB (0.41) | HSD17B10CYP3A4MAPTCYP2C9CYP2C19 | |
| SCHEMBL26754370 | 0.83 | HSD17B10 (0.46) | HSD17B10CYP3A4MAPTCYP2C9CYP2C19 | |
| SCHEMBL15964162 | 0.81 | TSHR (0.50) | TSHRPOLBPOLA1CA12CA14 | |
| SCHEMBL10285411 | 0.76 | HSD17B10 (0.44) | HSD17B10CYP3A4MAPTCYP2C9CYP2C19 | |
| SCHEMBL14827529 | 0.75 | NAAA (0.53) | TSHRPRKCA | |
| SCHEMBL5574367 | 0.74 | HSD17B10 (0.42) | HSD17B10CYP3A4MAPTCYP2C9CYP2C19 | |
| SCHEMBL9260657 | 0.74 | — | — | |
| SCHEMBL10448832 | 0.73 | KAT2A (0.33) | KAT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180065895-A1 | PROCESS FOR PREPARING A STORAGE-STABLE SILICONE RESIN | ELKEM SILICONES FRANCE SAS (FR) | 2018-03-08 | — | — | US | disclosed |