Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HTR2A | P28223 | 4/20 | 0.32 |
| ▸ | HTR2C | P28335 | 3/20 | 0.32 |
| ▸ | HTR2B | P41595 | 3/20 | 0.32 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | THPO | P40225 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13259162 | 0.78 | KDM4E (0.51) | MAPTKDM4ENPSR1HTTHTR2A | |
| SCHEMBL19929706 | 0.75 | MEN1 (0.33) | MEN1ALDH1A1KMT2A | |
| SCHEMBL19929708 | 0.71 | ALDH1A1 (0.33) | KDM4ECYP1A2CYP2C9CYP2C19MEN1 | |
| SCHEMBL19929694 | 0.71 | KDM4E (0.39) | KDM4ENPSR1HTR2AHTR2CHTR2B | |
| SCHEMBL1276464 | 0.68 | CYP1A2 (0.56) | MAPTKDM4ENPSR1HTTHTR2A | |
| SCHEMBL19929701 | 0.68 | KDM4E (0.36) | KDM4EHTR2ALMNACYP1A2CYP3A4 | |
| SCHEMBL27697273 | 0.67 | NPC1 (0.37) | KDM4EHTR2AHTR2CSIGMAR1CYP1A2 | |
| SCHEMBL487465 | 0.66 | MAPT (0.56) | MAPTNPSR1HTTLMNACYP1A2 | |
| Phenol SCHEMBL11797155 | 0.65 | CA12 (0.50) | MAPTLMNACYP1A2CYP2C19ALDH1A1 | |
| SCHEMBL27991909 | 0.65 | NPC1 (0.35) | NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10287225-B2 | Chain multiyne compound, preparation method and application thereof | XIAMEN UNIVERSITY (CN) | 2019-05-14 | — | — | US | disclosed |
| US-20180065908-A1 | CHAIN MULTIYNE COMPOUND, PREPARATION METHOD AND APPLICATION THEREOF | XIAMEN UNIVERSITY (CN) | 2018-03-08 | — | — | US | disclosed |
| US-20180065908-A1 | CHAIN MULTIYNE COMPOUND, PREPARATION METHOD AND APPLICATION THEREOF | XIAMEN UNIVERSITY (CN) | 2018-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180065908-A1 | CHAIN MULTIYNE COMPOUND, PREPARATION METHOD AND APPLICATION THEREOF | SQLE, COASY, MCCC2 | MAPT 4110/4885KDM4E 2838/4885NPSR1 3871/4885 |
| US-10287225-B2 | Chain multiyne compound, preparation method and application thereof | SQLE, COASY, MCCC2 | MAPT 4110/4885KDM4E 2838/4885NPSR1 3871/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.