Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.66 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CASP1 | P29466 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.47 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.47 |
| ▸ | MGLL | Q99685 | 1/20 | 0.46 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.45 |
| ▸ | ESR1 | P03372 | 2/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9165352 | 0.92 | TSHR (0.55) | KCNH2EPHX1TSHRKCNJ1CHRM2 | |
| SCHEMBL8727026 | 0.92 | TSHR (0.55) | KCNH2EPHX1TSHRKCNJ1CHRM2 | |
| SCHEMBL11308396 | 0.92 | TSHR (0.55) | KCNH2EPHX1TSHRKCNJ1CHRM2 | |
| SCHEMBL4310058 | 0.91 | KCNH2 (0.77) | KCNH2TSHRALDH1A1LMNACYP3A4 | |
| SCHEMBL8743949 | 0.91 | KCNH2 (0.77) | KCNH2TSHRALDH1A1LMNACYP3A4 | |
| SCHEMBL25174460 | 0.91 | KCNH2 (0.77) | KCNH2TSHRALDH1A1LMNACYP3A4 | |
| SCHEMBL1881781 | 0.91 | KCNH2 (0.77) | KCNH2TSHRALDH1A1LMNACYP3A4 | |
| SCHEMBL4190401 | 0.91 | KCNH2 (0.77) | KCNH2TSHRALDH1A1LMNACYP3A4 | |
| SCHEMBL25171490 | 0.91 | KCNH2 (0.77) | KCNH2TSHRALDH1A1LMNACYP3A4 | |
| SCHEMBL11075250 | 0.91 | KCNH2 (0.77) | KCNH2TSHRALDH1A1LMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180067361-A1 | LIQUID CRYSTAL DISPLAY DEVICE | SHARP KABUSHIKI KAISHA | 2018-03-08 | — | — | US | disclosed |