Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.44 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.36 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19930237 | 1.00 | AR (0.47) | ARHTTHIF1AFFAR1KMT2A | |
| SCHEMBL19930233 | 1.00 | AR (0.47) | ARHTTHIF1AFFAR1KMT2A | |
| SCHEMBL26396109 | 1.00 | AR (0.47) | ARHTTHIF1AFFAR1KMT2A | |
| SCHEMBL19930235 | 1.00 | AR (0.47) | ARHTTHIF1AFFAR1KMT2A | |
| SCHEMBL10284757 | 0.91 | HTT (0.51) | ARHTTHIF1AFFAR1KMT2A | |
| SCHEMBL19482760 | 0.86 | AR (0.55) | ARHTTHIF1AFFAR1KMT2A | |
| SCHEMBL801370 | 0.84 | HTT (0.47) | ARHTTHIF1AFFAR1KMT2A | |
| SCHEMBL19930223 | 0.84 | AR (0.56) | ARHTTHIF1AFFAR1KMT2A | |
| SCHEMBL19930224 | 0.84 | AR (0.56) | ARHTTHIF1AFFAR1KMT2A | |
| SCHEMBL19930222 | 0.84 | AR (0.56) | ARHTTHIF1AFFAR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11779550-B2 | Bisphenol ether derivatives and methods for using the same | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2023-10-10 | — | — | US | disclosed |
| US-20180064657-A1 | BISPHENOL ETHER DERIVATIVES AND METHODS FOR USING THE SAME | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2018-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180064657-A1 | BISPHENOL ETHER DERIVATIVES AND METHODS FOR USING THE SAME | AR, SHBG, ESRRA | AR 1/4885HTT 4135/4885HIF1A 3212/4885 |
| US-11779550-B2 | Bisphenol ether derivatives and methods for using the same | AR, SHBG, ESRRA | AR 1/4885HTT 4146/4885HIF1A 3256/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.