SCHEMBL1993063

SCHEMBL1993063

FC(Cl)C(F)(F)C(Cl)(Cl)Cl

nearest known ligand 0.32

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.32
HSD17B10 Q99714 1/20 0.32
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10377787 0.81 ALDH1A1 (0.38) ALDH1A1HSD17B10MEN1KMT2A
SCHEMBL64666 0.79 ALDH1A1 (0.32) ALDH1A1HSD17B10MEN1KMT2A
SCHEMBL1991322 0.79 ALDH1A1 (0.32) ALDH1A1HSD17B10MEN1KMT2A
SCHEMBL10800642 0.76
SCHEMBL250358 0.74 ALDH1A1 (0.33) ALDH1A1HSD17B10MEN1KMT2A
SCHEMBL251006 0.74 KDM4E (0.35)
SCHEMBL10376225 0.74 ALDH1A1 (0.33) ALDH1A1HSD17B10MEN1KMT2A
SCHEMBL1995255 0.74 ALDH1A1 (0.33) ALDH1A1HSD17B10
SCHEMBL10377773 0.74 ALDH1A1 (0.33) ALDH1A1HSD17B10MEN1KMT2A
SCHEMBL10377777 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10899688-B2 Method for producing and purifying 2,3,3,3-tetrafluoro-1-propene ARKEMA FRANCE (FR) 2021-01-26 US claimed
US-20170333941-A1 HIGH ENERGY EFFICIENCY PHASE CHANGE DEVICE USING CONVEX SURFACE FEATURES U.S. DEPARTMENT OF ENERGY 2017-11-23 US claimed
JP-2202825-A None JP disclosed
JP-2204444-A None JP disclosed
EP-3394017-B1 METHOD FOR PREPARING 2,3,3,3-TETRAFLUORO-1-PROPENE AND RECYCLING 2-CHLORO-3,3,3-TRIFLUOROPROPENE FREE OF IMPURITIES ARKEMA FRANCE (FR) 2023-10-25 EP disclosed
EP-3394014-B1 METHOD FOR PRODUCING AND PURIFYING 2,3,3,3-TETRAFLUORO-1-PROPENE ARKEMA FRANCE (FR) 2023-10-18 EP disclosed
EP-3394016-B1 METHOD FOR PRODUCING AND PURIFYING 2,3,3,3-TETRAFLUORO-1-PROPENE ARKEMA FRANCE (FR) 2023-05-10 EP disclosed
US-11299446-B2 Method for producing and purifying 2,3,3,3-tetrafluoro-1-propene ARKEMA FRANCE (FR) 2022-04-12 US disclosed
US-20210101854-A1 Method for producing and purifying 2,3,3,3-tetrafluoro-1-propene ARKEMA FRANCE (FR) 2021-04-08 US disclosed
US-10899688-B2 Method for producing and purifying 2,3,3,3-tetrafluoro-1-propene ARKEMA FRANCE (FR) 2021-01-26 US disclosed
US-10899689-B2 Method for purifying 2-chloro-3,3,3-trifluoropropene and method for preparing 2,3,3,3-tetrafluoro-1-propene ARKEMA FRANCE (FR) 2021-01-26 US disclosed
US-5264639-A Fluorination of chlorine containing 2,2-halogenopropane with hydrogen fluoride ASAHI GLASS COMPANY LTD. (JP) 1993-11-23 US disclosed
EP-0416113-A1 PROCESS FOR PRODUCING A HYDROGEN-CONTAINING 2,2-DIFLUOROPROPANE. ASAHI GLASS CO LTD (JP) 1991-03-13 EP disclosed
EP-0407619-A1 PROCESS FOR PRODUCING A CHLORINE-CONTAINING 2,2-DIFLUOROPROPANE ASAHI GLASS COMPANY LTD. (JP) 1991-01-16 EP disclosed
EP-0407622-A1 PROCESS FOR PRODUCING A 2,2-DIFLUOROPROPANE. ASAHI GLASS CO LTD (JP) 1991-01-16 EP disclosed
JP-H02204444-A PRODUCTION OF HYDROGEN-CONTAINING TRIFLUOROPROPANES AND HYDROGEN-CONTAINING DIFLUOROPROPANES ASAHI GLASS CO LTD 1990-08-14 JP disclosed
JP-H02202825-A 1,1,1-TRICHLORO-2,2,3-TRIFLUOROPROPANE ASAHI GLASS CO LTD 1990-08-10 JP disclosed
WO-1990008753-A1 PROCESS FOR PRODUCING A HYDROGEN-CONTAINING 2,2-DIFLUOROPROPANE ASAHI GLASS COMPANY LTD. (JP) 1990-08-09 WO disclosed
WO-1990008752-A1 PROCESS FOR PRODUCING A CHLORINE-CONTAINING 2,2-DIFLUOROPROPANE ASAHI GLASS COMPANY LTD. (JP) 1990-08-09 WO disclosed
WO-1990008754-A2 PROCESS FOR PRODUCING A 2,2-DIFLUOROPROPANE ASAHI GLASS COMPANY LTD. (JP) 1990-08-09 WO disclosed