Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 6/20 | 0.43 |
| ▸ | USP2 | O75604 | 6/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.43 |
| ▸ | CASP1 | P29466 | 6/20 | 0.43 |
| ▸ | CASP7 | P55210 | 6/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 4/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | BRD4 | O60885 | 12/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.38 |
| ▸ | HBB | P68871 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25043383 | 0.94 | MEN1 (0.40) | MEN1USP2CYP1A2CASP1CASP7 | |
| SCHEMBL19930864 | 0.93 | BRD4 (0.43) | MEN1USP2CYP1A2CASP1CASP7 | |
| SCHEMBL16650709 | 0.83 | BRD4 (0.49) | MEN1USP2CYP1A2CASP1CASP7 | |
| SCHEMBL29848858 | 0.83 | BRD4 (0.49) | MEN1USP2CYP1A2CASP1CASP7 | |
| SCHEMBL19930778 | 0.80 | CDK5 (0.49) | MEN1USP2CYP1A2CASP1CASP7 | |
| SCHEMBL19931265 | 0.79 | BRD4 (0.40) | MEN1USP2CYP1A2CASP1CASP7 | |
| SCHEMBL29848848 | 0.78 | BRD4 (0.47) | MEN1USP2CYP1A2CASP1CASP7 | |
| SCHEMBL16651985 | 0.78 | BRD4 (0.47) | MEN1USP2CYP1A2CASP1CASP7 | |
| SCHEMBL29848819 | 0.78 | BRD4 (0.43) | MEN1USP2CYP1A2CASP1CASP7 | |
| SCHEMBL29848814 | 0.78 | BRD4 (0.43) | MEN1USP2CYP1A2CASP1CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4134364-A2 | BROMODOMAIN INHIBITORS | Celgene Quanticel Research, Inc. (US) | 2023-02-15 | — | — | EP | disclosed |
| EP-3640241-A1 | BROMODOMAIN INHIBITORS | Celgene Quanticel Research, Inc. (US) | 2020-04-22 | — | — | EP | disclosed |
| EP-3290407-A1 | BROMODOMAIN INHIBITORS | Celgene Quanticel Research, Inc (US) | 2018-03-07 | — | — | EP | disclosed |