Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.32 |
| ▸ | EP300 | Q09472 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 2/20 | 0.32 |
| ▸ | AR | P10275 | 1/20 | 0.30 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19930893 | 0.87 | BRD4 (0.35) | BRD4EP300ARPTGDR2 | |
| SCHEMBL19930964 | 0.86 | BRD4 (0.33) | BRD4EP300ARPTGDR2 | |
| SCHEMBL19931222 | 0.86 | BRD4 (0.33) | BRD4EP300ARPTGDR2 | |
| SCHEMBL19930750 | 0.82 | BRD4 (0.36) | BRD4EP300CNR2PTGDR2 | |
| SCHEMBL19931208 | 0.79 | BRD4 (0.30) | BRD4EP300AR | |
| SCHEMBL19931105 | 0.78 | BRD4 (0.35) | BRD4EP300 | |
| SCHEMBL25043121 | 0.75 | BRD4 (0.34) | BRD4EP300AR | |
| SCHEMBL19930995 | 0.75 | BRD4 (0.34) | BRD4EP300AR | |
| SCHEMBL19930940 | 0.75 | BRD4 (0.31) | BRD4EP300 | |
| SCHEMBL19930879 | 0.74 | PTGER1 (0.34) | BRD4EP300 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4134364-A2 | BROMODOMAIN INHIBITORS | Celgene Quanticel Research, Inc. (US) | 2023-02-15 | — | — | EP | disclosed |
| EP-3640241-A1 | BROMODOMAIN INHIBITORS | Celgene Quanticel Research, Inc. (US) | 2020-04-22 | — | — | EP | disclosed |
| EP-3290407-A1 | BROMODOMAIN INHIBITORS | Celgene Quanticel Research, Inc (US) | 2018-03-07 | — | — | EP | disclosed |