Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5 | Q00535 | 2/20 | 0.47 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.47 |
| ▸ | BRD4 | O60885 | 11/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19930778 | 0.93 | CDK5 (0.49) | CDK5CDK5R1BRD4 | |
| SCHEMBL16650977 | 0.84 | BRD4 (0.41) | BRD4 | |
| SCHEMBL29848742 | 0.84 | BRD4 (0.41) | BRD4 | |
| SCHEMBL25043383 | 0.81 | MEN1 (0.40) | BRD4 | |
| SCHEMBL16651985 | 0.81 | BRD4 (0.47) | BRD4 | |
| SCHEMBL29848848 | 0.81 | BRD4 (0.47) | BRD4 | |
| SCHEMBL29848819 | 0.76 | BRD4 (0.43) | BRD4 | |
| SCHEMBL16650386 | 0.76 | BRD4 (0.43) | BRD4 | |
| SCHEMBL29848814 | 0.76 | BRD4 (0.43) | BRD4 | |
| SCHEMBL29848858 | 0.74 | BRD4 (0.49) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3640241-A1 | BROMODOMAIN INHIBITORS | Celgene Quanticel Research, Inc. (US) | 2020-04-22 | — | — | EP | disclosed |
| EP-3290407-A1 | BROMODOMAIN INHIBITORS | Celgene Quanticel Research, Inc (US) | 2018-03-07 | — | — | EP | disclosed |