Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 5/20 | 0.36 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.36 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.36 |
| ▸ | BRD9 | Q9H8M2 | 4/20 | 0.34 |
| ▸ | BRD4 | O60885 | 3/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.34 |
| ▸ | BRD2 | P25440 | 1/20 | 0.33 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19931013 | 0.94 | PDE4B (0.37) | PDE4BCREBBPBRD9BRD4PDE10A | |
| SCHEMBL19930969 | 0.86 | BRD4 (0.38) | CREBBPBRD9BRD4 | |
| SCHEMBL16651614 | 0.82 | BRD4 (0.44) | PDE4BTLR8CREBBPBRD9BRD4 | |
| SCHEMBL29848786 | 0.82 | BRD4 (0.44) | PDE4BTLR8CREBBPBRD9BRD4 | |
| SCHEMBL16651201 | 0.80 | CREBBP (0.37) | PDE4BCREBBPBRD4PDE10A | |
| SCHEMBL29848696 | 0.80 | CREBBP (0.37) | PDE4BCREBBPBRD4PDE10A | |
| SCHEMBL19931263 | 0.79 | BRD4 (0.39) | CREBBPBRD4ADORA2A | |
| SCHEMBL19930761 | 0.79 | BRD4 (0.39) | CREBBPBRD9BRD4 | |
| SCHEMBL25043154 | 0.78 | CREBBP (0.40) | CREBBPBRD4 | |
| SCHEMBL16651731 | 0.76 | BRD4 (0.46) | PDE4BCREBBPBRD9BRD4PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4134364-A2 | BROMODOMAIN INHIBITORS | Celgene Quanticel Research, Inc. (US) | 2023-02-15 | — | — | EP | disclosed |
| EP-3640241-A1 | BROMODOMAIN INHIBITORS | Celgene Quanticel Research, Inc. (US) | 2020-04-22 | — | — | EP | disclosed |
| EP-3290407-A1 | BROMODOMAIN INHIBITORS | Celgene Quanticel Research, Inc (US) | 2018-03-07 | — | — | EP | disclosed |