Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 20/20 | 0.58 |
| ▸ | BRD2 | P25440 | 1/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.47 |
| ▸ | TSPO | P30536 | 1/20 | 0.47 |
| ▸ | EP300 | Q09472 | 1/20 | 0.47 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.47 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19931069 | 0.90 | BRD4 (0.60) | BRD4BRD2ADORA2BTSPOEP300 | |
| SCHEMBL16651239 | 0.86 | BRD4 (0.66) | BRD4BRD2ADORA2BTSPOEP300 | |
| SCHEMBL16650620 | 0.84 | BRD4 (0.80) | BRD4BRD2ADORA2BTSPOEP300 | |
| SCHEMBL19930662 | 0.82 | BRD4 (0.56) | BRD4 | |
| SCHEMBL25043114 | 0.81 | BRD4 (0.58) | BRD4BRD2BRD3BRDT | |
| SCHEMBL25043127 | 0.81 | BRD4 (0.64) | BRD4BRD2BRD3BRDT | |
| SCHEMBL21968479 | 0.81 | BRD4 (0.73) | BRD4 | |
| SCHEMBL21969250 | 0.81 | BRD4 (0.73) | BRD4BRD2ADORA2BTSPOEP300 | |
| SCHEMBL21968015 | 0.81 | BRD4 (0.73) | BRD4 | |
| SCHEMBL25043109 | 0.79 | BRD4 (0.77) | BRD4BRD2ADORA2BTSPOEP300 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4134364-A2 | BROMODOMAIN INHIBITORS | Celgene Quanticel Research, Inc. (US) | 2023-02-15 | — | — | EP | disclosed |
| EP-3640241-A1 | BROMODOMAIN INHIBITORS | Celgene Quanticel Research, Inc. (US) | 2020-04-22 | — | — | EP | disclosed |
| EP-3290407-A1 | BROMODOMAIN INHIBITORS | Celgene Quanticel Research, Inc (US) | 2018-03-07 | — | — | EP | disclosed |