Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2B | P41595 | 7/20 | 0.48 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.48 |
| ▸ | HTR3B | O95264 | 1/20 | 0.48 |
| ▸ | HTR3A | P46098 | 1/20 | 0.48 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.48 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.48 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 6/20 | 0.45 |
| ▸ | HTR2A | P28223 | 5/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CAMK2D | Q13557 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10554268 | 0.83 | TSHR (0.56) | TSHRALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL18627089 | 0.82 | HTR2B (0.44) | HTR2BHTR3EHTR3BHTR3ATMEM97 | |
| SCHEMBL19539757 | 0.81 | TSHR (0.52) | TSHRALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL20703764 | 0.80 | HTR2B (0.44) | HTR2BHTR3EHTR3BHTR3ATMEM97 | |
| SCHEMBL29547200 | 0.79 | HTR2B (0.37) | HTR2BHTR3EHTR3BHTR3ATMEM97 | |
| SCHEMBL14312250 | 0.79 | HTR2B (0.44) | HTR2BHTR3EHTR3BHTR3ATMEM97 | |
| SCHEMBL14312249 | 0.79 | HTR2B (0.44) | HTR2BHTR3EHTR3BHTR3ATMEM97 | |
| SCHEMBL24717656 | 0.78 | RAB9A (0.39) | HTR2BHTR2CHTR2ATSHRALDH1A1 | |
| SCHEMBL21163305 | 0.78 | TSHR (0.42) | TSHRALDH1A1RAB9AMEN1KMT2A | |
| SCHEMBL25648819 | 0.78 | TSHR (0.42) | TSHRALDH1A1RAB9AMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2885302-B1 | PROCESS FOR THE PREPARATION OF DIPEPTIDYLPEPTIDASE INHIBITORS | GLENMARK PHARMACEUTICALS LTD (IN) | 2018-03-07 | — | — | EP | disclosed |