Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 6/20 | 0.54 |
| ▸ | CCNC | P24863 | 3/20 | 0.46 |
| ▸ | CDK8 | P49336 | 3/20 | 0.46 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.41 |
| ▸ | AURKA | O14965 | 2/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.40 |
| ▸ | CNR1 | P21554 | 1/20 | 0.39 |
| ▸ | CNR2 | P34972 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21545781 | 0.90 | CHRM1 (0.61) | CHRM1 | |
| SCHEMBL19932682 | 0.88 | CHRM1 (0.57) | CHRM1CCNCCDK8PIK3CDAURKA | |
| SCHEMBL19932607 | 0.87 | CNR2 (0.46) | CHRM1CNR1CNR2 | |
| SCHEMBL19932685 | 0.85 | NPC1 (0.46) | CHRM1CNR1CNR2 | |
| SCHEMBL19932715 | 0.84 | CHRM1 (0.43) | CHRM1CNR1CNR2 | |
| SCHEMBL19932684 | 0.84 | CHRM1 (0.42) | CHRM1CNR1 | |
| SCHEMBL19932588 | 0.83 | CHRM1 (0.51) | CHRM1 | |
| SCHEMBL22212669 | 0.81 | IDH1 (0.39) | — | |
| SCHEMBL21935357 | 0.80 | CHRM1 (0.64) | CHRM1CCNCCDK8 | |
| SCHEMBL19932678 | 0.80 | PARP1 (0.39) | CHRM1CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018042362-A1 | MUSCARINIC M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS | SUVEN LIFE SCIENCES LIMITED (IN) | 2018-03-08 | — | — | WO | disclosed |