Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 7/20 | 0.57 |
| ▸ | CCNC | P24863 | 2/20 | 0.47 |
| ▸ | CDK8 | P49336 | 2/20 | 0.47 |
| ▸ | AURKA | O14965 | 2/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 2/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22212626 | 0.89 | CHRM1 (0.44) | CHRM1PIK3CD | |
| SCHEMBL19932681 | 0.89 | CHRM1 (0.64) | CHRM1 | |
| SCHEMBL19932680 | 0.88 | CHRM1 (0.54) | CHRM1CCNCCDK8AURKAAURKB | |
| SCHEMBL19932608 | 0.84 | CHRM1 (0.45) | CHRM1CCNCCDK8 | |
| SCHEMBL19932610 | 0.83 | CHRM1 (0.46) | CHRM1CCNCCDK8 | |
| SCHEMBL22212621 | 0.83 | NPC1 (0.48) | CNR1CNR2 | |
| SCHEMBL21935357 | 0.82 | CHRM1 (0.64) | CHRM1CCNCCDK8 | |
| SCHEMBL22212650 | 0.82 | NPC1 (0.49) | CNR1CNR2 | |
| SCHEMBL19932652 | 0.81 | CHRM1 (0.42) | CHRM1CNR1CNR2 | |
| SCHEMBL22212639 | 0.80 | CHRM1 (0.69) | CHRM1CCNCCDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3507289-B1 | MUSCARINIC M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS | SUVEN LIFE SCIENCES LTD (IN) | 2020-07-15 | — | — | EP | disclosed |
| WO-2018042362-A1 | MUSCARINIC M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS | SUVEN LIFE SCIENCES LIMITED (IN) | 2018-03-08 | — | — | WO | disclosed |