Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 10/20 | 0.44 |
| ▸ | CNR1 | P21554 | 9/20 | 0.44 |
| ▸ | ABHD12 | Q8N2K0 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 1/20 | 0.40 |
| ▸ | HPGDS | O60760 | 1/20 | 0.39 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.39 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.39 |
| ▸ | DNMT3A | Q9Y6K1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19932701 | 0.90 | CHRM1 (0.43) | CNR2CNR1 | |
| SCHEMBL28496304 | 0.90 | CHRM1 (0.43) | CNR2CNR1 | |
| SCHEMBL19932632 | 0.85 | CNR2 (0.47) | CNR2CNR1ABHD12DPP4ABHD6 | |
| SCHEMBL19925934 | 0.85 | PTGER4 (0.43) | CNR2CNR1PARP1HPGDS | |
| SCHEMBL19932597 | 0.82 | ADORA1 (0.44) | CNR2CNR1PARP1HPGDS | |
| SCHEMBL22212648 | 0.78 | CNR2 (0.48) | CNR2CNR1ABHD12DPP4ABHD6 | |
| SCHEMBL21545782 | 0.77 | CHRM1 (0.47) | — | |
| SCHEMBL19932638 | 0.76 | CNR2 (0.46) | CNR2CNR1ABHD12PARP1DPP4 | |
| SCHEMBL19932635 | 0.74 | CHRM1 (0.49) | — | |
| SCHEMBL19932547 | 0.73 | CHRM1 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3507289-B1 | MUSCARINIC M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS | SUVEN LIFE SCIENCES LTD (IN) | 2020-07-15 | — | — | EP | disclosed |
| WO-2018042362-A1 | MUSCARINIC M1 RECEPTOR POSITIVE ALLOSTERIC MODULATORS | SUVEN LIFE SCIENCES LIMITED (IN) | 2018-03-08 | — | — | WO | disclosed |