Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 12/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.40 |
| ▸ | CNR2 | P34972 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.38 |
| ▸ | CCR3 | P51677 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19932701 | 1.00 | CHRM1 (0.43) | CHRM1CNR1CNR2CYP2D6CCR3 | |
| SCHEMBL19932702 | 0.90 | CNR2 (0.44) | CNR1CNR2 | |
| SCHEMBL21545782 | 0.88 | CHRM1 (0.47) | CHRM1 | |
| SCHEMBL19932635 | 0.86 | CHRM1 (0.49) | CHRM1 | |
| SCHEMBL19932547 | 0.84 | CHRM1 (0.46) | CHRM1 | |
| SCHEMBL19925934 | 0.83 | PTGER4 (0.43) | CNR1CNR2 | |
| SCHEMBL19932597 | 0.80 | ADORA1 (0.44) | CNR1CNR2 | |
| SCHEMBL19932705 | 0.79 | CHRM1 (0.51) | CHRM1 | |
| SCHEMBL28904624 | 0.78 | CHRM1 (0.61) | CHRM1 | |
| SCHEMBL19932658 | 0.78 | CHRM1 (0.61) | CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109952302-B | Positive allosteric modulators of muscarinic M1 receptors | 苏文生命科学有限公司 | 2020-11-24 | — | — | CN | disclosed |