Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 6/20 | 0.51 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.51 |
| ▸ | KDM5B | Q9UGL1 | 4/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | KDM5A | P29375 | 2/20 | 0.38 |
| ▸ | KDM6B | O15054 | 1/20 | 0.38 |
| ▸ | KDM5C | P41229 | 1/20 | 0.38 |
| ▸ | KDM5D | Q9BY66 | 1/20 | 0.38 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.38 |
| ▸ | PHF8 | Q9UPP1 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19933295 | 0.87 | ADORA3 (0.51) | ADORA3ADORA1KDM5BALDH1A1KDM4E | |
| SCHEMBL19933292 | 0.79 | KDM5B (0.48) | ADORA3ADORA1KDM5BALDH1A1KDM4E | |
| SCHEMBL23921090 | 0.76 | ADORA3 (0.51) | ADORA3ADORA1KDM5BALDH1A1KDM4E | |
| SCHEMBL19779666 | 0.74 | KDM5B (0.43) | ADORA3ADORA1KDM5BALDH1A1KDM4E | |
| SCHEMBL24775341 | 0.74 | ADORA3 (0.47) | ADORA3ADORA1ALDH1A1KDM4EHPGD | |
| SCHEMBL18088765 | 0.72 | ADORA3 (0.48) | ADORA3ADORA1ALDH1A1KDM4EHPGD | |
| SCHEMBL21396327 | 0.72 | ADORA3 (0.42) | ADORA3ADORA1KDM5BMAPTKMT2A | |
| SCHEMBL23920903 | 0.68 | ADORA3 (0.48) | ADORA3ADORA1ALDH1A1KDM4EHPGD | |
| SCHEMBL14016217 | 0.68 | ADORA3 (1.00) | ADORA3ADORA1 | |
| SCHEMBL21396368 | 0.68 | ADORA3 (0.39) | ADORA3ADORA1KDM5BALDH1A1KDM5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018041942-A9 | NEW POLYMER LINKED MULTIMERS OF GUANOSINE-3', 5'-CYCLIC MONOPHOSPHATES | MIRECA MEDICINES GMBH (DE) | 2019-01-17 | — | — | WO | disclosed |
| WO-2018041942-A1 | NEW POLYMER LINKED MULTIMERS OF GUANOSINE-3', 5'-CYCLIC MONOPHOSPHATES | BIOLOG LIFE SCIENCE INSTITUTE FORSCHUNGSLABOR UND BIOCHEMICA-VERTRIEB GMBH (DE) | 2018-03-08 | — | — | WO | disclosed |