Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PPM1B | O75688 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | PPP1CC | P36873 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | TLR4 | O00206 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29205339 | 0.71 | ALDH1A1 (0.41) | ALDH1A1TSHRPPM1BPTPN1PPP1CC | |
| SCHEMBL31555465 | 0.71 | PPM1B (0.43) | ALDH1A1TSHRPPM1BPTPN1PPP1CC | |
| SCHEMBL19933374 | 0.69 | ALDH1A1 (0.42) | ALDH1A1TDP1TSHRSMN1; SMN2PPM1B | |
| SCHEMBL19933346 | 0.69 | ALDH1A1 (0.42) | ALDH1A1TDP1TSHRSMN1; SMN2PPM1B | |
| SCHEMBL25756047 | 0.67 | ALDH1A1 (0.58) | ALDH1A1TDP1TSHRSMN1; SMN2 | |
| SCHEMBL13951299 | 0.65 | SMN1; SMN2 (0.50) | ALDH1A1TDP1TSHRSMN1; SMN2KDM4E | |
| SCHEMBL2623200 | 0.65 | TSHR (0.82) | ALDH1A1TDP1TSHRSMN1; SMN2KMT2A | |
| SCHEMBL15467643 | 0.64 | TSHR (0.64) | ALDH1A1TDP1TSHRSMN1; SMN2 | |
| SCHEMBL10071426 | 0.63 | TSHR (0.78) | ALDH1A1TDP1TSHRSMN1; SMN2 | |
| SCHEMBL10071427 | 0.63 | TSHR (0.78) | ALDH1A1TDP1TSHRSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018041930-A1 | ADHESIVES BASED ON GAMMA-LACTONES | HENKEL AG & CO. KGAA (DE) | 2018-03-08 | — | — | WO | disclosed |