Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | PLA2G10 | O15496 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19933750 | 0.92 | MEN1 (0.40) | KDM4EL3MBTL1ATMRXFP1MEN1 | |
| SCHEMBL19039404 | 0.89 | L3MBTL1 (0.44) | KDM4EL3MBTL1ATMRXFP1MEN1 | |
| SCHEMBL23370525 | 0.89 | L3MBTL1 (0.44) | KDM4EL3MBTL1ATMRXFP1MEN1 | |
| SCHEMBL21742779 | 0.88 | L3MBTL1 (0.39) | KDM4EL3MBTL1ATMRXFP1MEN1 | |
| SCHEMBL18505367 | 0.88 | L3MBTL1 (0.47) | KDM4EL3MBTL1ATMRXFP1MEN1 | |
| SCHEMBL23606166 | 0.88 | KDM4E (0.46) | KDM4EL3MBTL1ATMRXFP1MEN1 | |
| SCHEMBL17995360 | 0.86 | L3MBTL1 (0.46) | KDM4EL3MBTL1ATMRXFP1MEN1 | |
| SCHEMBL16674256 | 0.86 | L3MBTL1 (0.46) | KDM4EL3MBTL1ATMRXFP1MEN1 | |
| SCHEMBL20315796 | 0.86 | ATM (0.42) | KDM4EL3MBTL1ATMRXFP1MEN1 | |
| SCHEMBL25966442 | 0.86 | L3MBTL1 (0.50) | KDM4EL3MBTL1ATMRXFP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018041769-A1 | BINUCLEAR AND TRINUCLEAR METAL COMPLEXES COMPOSED OF TWO INTER-LINKED TRIPODAL HEXADENTATE LIGANDS FOR USE IN ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2018-03-08 | — | — | WO | disclosed |