Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19933822 | 0.90 | TP53 (0.56) | TP53MEN1KMT2A | |
| SCHEMBL19933819 | 0.89 | TP53 (0.52) | TP53 | |
| SCHEMBL19933936 | 0.84 | MEN1 (0.47) | MEN1KMT2A | |
| SCHEMBL19933963 | 0.83 | TP53 (0.50) | TP53 | |
| SCHEMBL19933959 | 0.83 | TP53 (0.52) | TP53KMT2A | |
| SCHEMBL19927136 | 0.81 | — | — | |
| SCHEMBL19933953 | 0.79 | MAPK14 (0.56) | — | |
| SCHEMBL19933831 | 0.78 | TP53 (0.48) | TP53 | |
| SCHEMBL19933946 | 0.78 | TP53 (0.48) | TP53 | |
| SCHEMBL19933881 | 0.78 | TP53 (0.43) | TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018045182-A1 | DISUBSTITUTED AND TRISUBTITUTED 1,2,3-TRIAZOLES AS WNT INHIBITORS | THE BOARD OF REGENTS OF HTE UNIVERSITY OF TEXAS SYSTEM (US) | 2018-03-08 | — | — | WO | disclosed |