Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19933823 | 0.91 | KDM4E (0.43) | — | |
| SCHEMBL19933816 | 0.90 | — | — | |
| SCHEMBL19927136 | 0.84 | — | — | |
| SCHEMBL19933935 | 0.84 | TP53 (0.50) | MEN1KMT2A | |
| SCHEMBL19933957 | 0.83 | KDM4E (0.41) | — | |
| SCHEMBL19933960 | 0.83 | CDC7 (0.46) | — | |
| SCHEMBL19933826 | 0.79 | HSP90AA1 (0.40) | — | |
| SCHEMBL19933952 | 0.79 | MAPK14 (0.58) | — | |
| SCHEMBL19933944 | 0.78 | HSP90AA1 (0.41) | — | |
| SCHEMBL19933882 | 0.78 | MAPK14 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018045182-A1 | DISUBSTITUTED AND TRISUBTITUTED 1,2,3-TRIAZOLES AS WNT INHIBITORS | THE BOARD OF REGENTS OF HTE UNIVERSITY OF TEXAS SYSTEM (US) | 2018-03-08 | — | — | WO | disclosed |