Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 17/20 | 0.68 |
| ▸ | AKR1C2 | P52895 | 17/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | CTSV | O60911 | 1/20 | 0.52 |
| ▸ | CTSL | P07711 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8773601 | 0.91 | AKR1C3 (0.81) | AKR1C3AKR1C2MEN1LMNAKMT2A | |
| SCHEMBL14598926 | 0.91 | AKR1C3 (0.81) | AKR1C3AKR1C2MEN1LMNAKMT2A | |
| SCHEMBL19934159 | 0.87 | MAPT (0.54) | AKR1C3AKR1C2MEN1KMT2AMAPT | |
| SCHEMBL1415572 | 0.85 | AKR1C3 (0.82) | AKR1C3AKR1C2MEN1LMNAKMT2A | |
| SCHEMBL8773607 | 0.85 | AKR1C3 (0.71) | AKR1C3AKR1C2MEN1LMNAKMT2A | |
| SCHEMBL9594769 | 0.84 | AKR1C3 (0.84) | AKR1C3AKR1C2MEN1LMNAKMT2A | |
| SCHEMBL9593591 | 0.81 | AKR1C3 (0.79) | AKR1C3AKR1C2MEN1LMNAKMT2A | |
| SCHEMBL9595705 | 0.81 | AKR1C3 (0.71) | AKR1C3AKR1C2MEN1LMNAKMT2A | |
| SCHEMBL9595156 | 0.81 | AKR1C3 (1.00) | AKR1C3AKR1C2MEN1LMNAKMT2A | |
| SCHEMBL14598923 | 0.81 | AKR1C3 (0.78) | AKR1C3AKR1C2MEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1646691-B2 | QUINACRIDONE PIGMENT COMPOSITIONS COMPRISING UNSYMMETRICALLY SUBSTITUTED COMPONENTS | BASF SE (DE) | 2018-03-07 | — | — | EP | disclosed |