Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL332013 | 0.95 | — | — | |
| SCHEMBL22908524 | 0.95 | — | — | |
| SCHEMBL4189676 | 0.80 | KDM4E (0.32) | TP53KDM4E | |
| SCHEMBL20820753 | 0.79 | TP53 (0.35) | TP53KDM4E | |
| SCHEMBL19934664 | 0.79 | KMT2A (0.37) | SIGMAR1SLC6A4 | |
| SCHEMBL21153869 | 0.78 | — | — | |
| SCHEMBL21153859 | 0.78 | — | — | |
| SCHEMBL19934794 | 0.78 | — | — | |
| SCHEMBL21077086 | 0.78 | SIGMAR1 (0.38) | SIGMAR1SLC6A4 | |
| SCHEMBL1741259 | 0.77 | SIGMAR1 (0.34) | SIGMAR1KDM4ESLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018041245-A1 | AMINO MERCAPTAN COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF IN PROTECTION AGAINST RADIATION | 中国医学科学院放射医学研究所 | 2018-03-08 | — | — | WO | disclosed |