Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 4/20 | 0.52 |
| ▸ | DPP8 | Q6V1X1 | 3/20 | 0.40 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | CTRB1 | P17538 | 5/20 | 0.38 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.37 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.34 |
| ▸ | FAP | Q12884 | 1/20 | 0.34 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.34 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.34 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | XIAP | P98170 | 1/20 | 0.32 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.32 |
| ▸ | MME | P08473 | 1/20 | 0.31 |
| ▸ | ACE | P12821 | 1/20 | 0.31 |
| ▸ | CPA1 | P15085 | 1/20 | 0.31 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1259207 | 1.00 | DPP4 (0.52) | DPP4DPP8DPP7PAX8CTRB1 | |
| SCHEMBL1259210 | 1.00 | DPP4 (0.52) | DPP4DPP8DPP7PAX8CTRB1 | |
| SCHEMBL3887774 | 1.00 | DPP4 (0.52) | DPP4DPP8DPP7PAX8CTRB1 | |
| SCHEMBL3499172 | 1.00 | DPP4 (0.52) | DPP4DPP8DPP7PAX8CTRB1 | |
| SCHEMBL30799680 | 0.95 | DPP4 (0.48) | DPP4DPP8DPP7PAX8CTRB1 | |
| SCHEMBL22598435 | 0.95 | DPP4 (0.48) | DPP4DPP8DPP7PAX8CTRB1 | |
| SCHEMBL25831212 | 0.95 | DPP4 (0.48) | DPP4DPP8DPP7PAX8CTRB1 | |
| SCHEMBL31181297 | 0.95 | DPP4 (0.48) | DPP4DPP8DPP7PAX8CTRB1 | |
| SCHEMBL30799820 | 0.95 | DPP4 (0.48) | DPP4DPP8DPP7PAX8CTRB1 | |
| Hydrochloric Acid SCHEMBL9134682 | 0.93 | DPP4 (0.47) | DPP4DPP8DPP7PAX8CTRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3508476-A1 | AMINO MERCAPTAN COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF IN PROTECTION AGAINST RADIATION | Inst Of Radiation Medicine Chinese Acad Of Medical Sciences (CN) | 2019-07-10 | — | — | EP | disclosed |
| WO-2018041245-A1 | AMINO MERCAPTAN COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF IN PROTECTION AGAINST RADIATION | 中国医学科学院放射医学研究所 | 2018-03-08 | — | — | WO | disclosed |