SCHEMBL30799680

SCHEMBL30799680

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nearest known ligand 0.48

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
DPP4 P27487 3/20 0.48
DPP8 Q6V1X1 3/20 0.38
DPP7 Q9UHL4 2/20 0.38
PAX8 Q06710 1/20 0.37
CTRB1 P17538 5/20 0.36
NOD1 Q9Y239 1/20 0.36
SLC15A1 P46059 1/20 0.33
ERAP2 Q6P179 1/20 0.33
ERAP1 Q9NZ08 1/20 0.33
LNPEP Q9UIQ6 1/20 0.33
DPP9 Q86TI2 2/20 0.32
FAP Q12884 1/20 0.32
TAAR1 Q96RJ0 1/20 0.32
XIAP P98170 1/20 0.30
BIRC2 Q13490 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22598435 1.00 DPP4 (0.48) DPP4DPP8DPP7PAX8CTRB1
SCHEMBL30799820 1.00 DPP4 (0.48) DPP4DPP8DPP7PAX8CTRB1
SCHEMBL31181297 1.00 DPP4 (0.48) DPP4DPP8DPP7PAX8CTRB1
SCHEMBL25831212 1.00 DPP4 (0.48) DPP4DPP8DPP7PAX8CTRB1
Hydrochloric Acid SCHEMBL9134682 0.98 DPP4 (0.47) DPP4DPP8DPP7PAX8CTRB1
SCHEMBL19934697 0.95 DPP4 (0.52) DPP4DPP8DPP7PAX8CTRB1
SCHEMBL1259210 0.95 DPP4 (0.52) DPP4DPP8DPP7PAX8CTRB1
SCHEMBL3887774 0.95 DPP4 (0.52) DPP4DPP8DPP7PAX8CTRB1
SCHEMBL3499172 0.95 DPP4 (0.52) DPP4DPP8DPP7PAX8CTRB1
SCHEMBL1259207 0.95 DPP4 (0.52) DPP4DPP8DPP7PAX8CTRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240116985-A1 STAPLED PEPTIDES AND METHODS THEREOF PARABILIS MEDICINES, INC. 2024-04-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240116985-A1 STAPLED PEPTIDES AND METHODS THEREOF CTNNB1, APC, CTNNA1 DPP4 552/4885DPP8 231/4885DPP7 349/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.