SCHEMBL19934813

SCHEMBL19934813

C[C@H](NC(=O)[C@@H](N)CS)C(=O)N[C@@H](CS)C(=O)O

nearest known ligand 0.59

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ACE P12821 1/20 0.59
KDM4E B2RXH2 1/20 0.50
MAPT P10636 1/20 0.50
THRB P10828 1/20 0.50
ALOX15 P16050 1/20 0.50
NFKB1 P19838 1/20 0.50
PTGS2 P35354 1/20 0.50
THPO P40225 1/20 0.50
RECQL P46063 1/20 0.50
BLM P54132 1/20 0.50
SMN1; SMN2 Q16637 1/20 0.50
PTGS1 P23219 2/20 0.44
SLC7A11 Q9UPY5 1/20 0.44
FNTA P49354 9/20 0.41
FNTB P49356 9/20 0.41
PGGT1B P53609 3/20 0.41
FOLH1 Q04609 1/20 0.40
GSTK1 Q9Y2Q3 1/20 0.38
MME P08473 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30011175 1.00 ACE (0.59) ACEKDM4EMAPTTHRBALOX15
SCHEMBL30010893 1.00 ACE (0.59) ACEKDM4EMAPTTHRBALOX15
SCHEMBL30011166 1.00 ACE (0.59) ACEKDM4EMAPTTHRBALOX15
SCHEMBL30931518 0.93 ACE (0.51) ACEKDM4EMAPTTHRBALOX15
SCHEMBL30685989 0.91 ACE (0.50) ACEKDM4EMAPTTHRBALOX15
SCHEMBL19196091 0.90 ACE (0.56) ACEKDM4EMAPTTHRBALOX15
SCHEMBL29461589 0.90 ACE (0.56) ACEKDM4EMAPTTHRBALOX15
SCHEMBL28101261 0.90 ACE (0.47) ACEKDM4EMAPTTHRBALOX15
SCHEMBL28101266 0.90 ACE (0.47) ACEKDM4EMAPTTHRBALOX15
SCHEMBL19379981 0.90 ACE (0.56) ACEKDM4EMAPTTHRBALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250345411-A1 VACCINATION IN NEWBORNS AND INFANTS CureVac SE (DE) 2025-11-13 US disclosed
US-20250345410-A1 VACCINATION IN NEWBORNS AND INFANTS CureVac SE (DE) 2025-11-13 US disclosed
US-12390520-B2 Vaccination in newborns and infants Cure Vac SE (DE) 2025-08-19 US disclosed
US-20240390478-A1 VACCINATION IN ELDERLY PATIENTS CureVac SE (DE) 2024-11-28 US disclosed
US-12036277-B2 Vaccination with mRNA-coded antigens CureVac SE (DE) 2024-07-16 US disclosed
US-20240197857-A1 VACCINATION WITH mRNA-CODED ANTIGENS CureVac SE (DE) 2024-06-20 US disclosed
US-11975064-B2 Vaccination with mRNA-coded antigens CureVac SE (DE) 2024-05-07 US disclosed
EP-3508476-B1 AMINO MERCAPTAN COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF IN PROTECTION AGAINST RADIATION SHANGHAI KECHOW PHARMA INC (CN) 2023-11-22 EP disclosed
US-20230302146-A1 HYBRID CARRIERS FOR NUCLEIC ACID CARGO CureVac SE (DE) 2023-09-28 US disclosed
US-20230285594-A1 COMPLEXATION OF NUCLEIC ACIDS WITH DISULFIDE-CROSSLINKED CATIONIC COMPONENTS FOR TRANSFECTION AND IMMUNOSTIMULATION CureVac SE (DE) 2023-09-14 US disclosed
US-20230233662-A1 VACCINATION IN NEWBORNS AND INFANTS CureVac SE (DE) 2023-07-27 US disclosed
US-11672856-B2 Vaccination in newborns and infants CureVac SE (DE) 2023-06-13 US disclosed
US-11478552-B2 Hybrid carriers for nucleic acid cargo CUREVAC AG (DE) 2022-10-25 US disclosed
WO-2018041245-A1 AMINO MERCAPTAN COMPOUND AND PREPARATION METHOD THEREFOR AND USE THEREOF IN PROTECTION AGAINST RADIATION 中国医学科学院放射医学研究所 2018-03-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11478552-B2 Hybrid carriers for nucleic acid cargo HNRNPH1, HNRNPH3, SNRPE ACE 4699/4885KDM4E 4808/4885MAPT 3024/4885
US-20250345410-A1 VACCINATION IN NEWBORNS AND INFANTS HLA-DRB1, TLR3, TLR9 ACE 4227/4885KDM4E 3834/4885MAPT 3792/4885
US-20230302146-A1 HYBRID CARRIERS FOR NUCLEIC ACID CARGO HNRNPH1, HNRNPH3, SNRPE ACE 4699/4885KDM4E 4808/4885MAPT 3024/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.