Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 16/20 | 0.58 |
| ▸ | PIK3CG | P48736 | 9/20 | 0.58 |
| ▸ | PIK3CA | P42336 | 6/20 | 0.58 |
| ▸ | PIK3CB | P42338 | 6/20 | 0.58 |
| ▸ | PRKDC | P78527 | 6/20 | 0.54 |
| ▸ | ABL1 | P00519 | 3/20 | 0.54 |
| ▸ | EGFR | P00533 | 3/20 | 0.54 |
| ▸ | HCK | P08631 | 3/20 | 0.54 |
| ▸ | SRC | P12931 | 3/20 | 0.54 |
| ▸ | KDR | P35968 | 3/20 | 0.54 |
| ▸ | MTOR | P42345 | 3/20 | 0.54 |
| ▸ | EPHB4 | P54760 | 3/20 | 0.54 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.54 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.47 |
| ▸ | FGFR2 | P21802 | 1/20 | 0.47 |
| ▸ | FGFR4 | P22455 | 1/20 | 0.47 |
| ▸ | FGFR3 | P22607 | 1/20 | 0.47 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19935751 | 0.92 | PIK3CD (0.60) | PIK3CDPIK3CGPIK3CAPIK3CBPRKDC | |
| SCHEMBL19935686 | 0.90 | PIK3CG (0.60) | PIK3CDPIK3CGPIK3CAPIK3CBPRKDC | |
| SCHEMBL19935678 | 0.88 | CSNK1E (0.59) | PIK3CDPIK3CGPIK3CAPIK3CBPRKDC | |
| SCHEMBL9884123 | 0.83 | PIK3CD (0.68) | PIK3CDPIK3CGPIK3CAPIK3CBPRKDC | |
| SCHEMBL9884094 | 0.82 | PIK3CD (0.78) | PIK3CDPIK3CGPIK3CAPIK3CBPRKDC | |
| SCHEMBL9884092 | 0.82 | PIK3CG (0.80) | PIK3CDPIK3CGPIK3CAPIK3CBPRKDC | |
| SCHEMBL19935812 | 0.82 | PIK3CD (0.75) | PIK3CDPIK3CGPIK3CAPIK3CBPRKDC | |
| SCHEMBL16347463 | 0.81 | PIK3CD (0.61) | PIK3CDPIK3CGPIK3CAPIK3CBPRKDC | |
| SCHEMBL17936598 | 0.81 | PIK3CD (0.61) | PIK3CDPIK3CGPIK3CAPIK3CBPRKDC | |
| SCHEMBL16386491 | 0.81 | PIK3CD (0.61) | PIK3CDPIK3CGPIK3CAPIK3CBPRKDC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3016955-B1 | PI3K PROTEIN KINASE INHIBITORS, PARTICULARLY DELTA AND/OR GAMMA INHIBITORS | RHIZEN PHARMACEUTICALS S A (CH) | 2018-03-07 | — | — | EP | disclosed |