Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | EZH2 | Q15910 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984611 | 0.91 | GAA (0.46) | GAATSHRPOLBKMT2AATM | |
| SCHEMBL7508238 | 0.89 | GAA (0.50) | GAATSHRPOLBKMT2AATM | |
| SCHEMBL12972581 | 0.89 | GAA (0.50) | GAATSHRPOLBKMT2AATM | |
| SCHEMBL7708866 | 0.87 | GAA (0.49) | GAATSHRPOLBKMT2AATM | |
| SCHEMBL31142 | 0.86 | GAA (0.51) | GAATSHRPOLBKMT2AATM | |
| SCHEMBL25475352 | 0.85 | GAA (0.47) | GAATSHRPOLBKMT2AATM | |
| SCHEMBL23871256 | 0.85 | GAA (0.47) | GAATSHRPOLBKMT2AATM | |
| SCHEMBL7518780 | 0.84 | GAA (0.46) | GAATSHRPOLBKMT2AATM | |
| SCHEMBL9617629 | 0.84 | GAA (0.46) | GAATSHRPOLBKMT2AATM | |
| SCHEMBL26785335 | 0.83 | GAA (0.49) | GAATSHRPOLBKMT2AATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2758462-B1 | STABILIZING OF ORGANIC MATERIAL WITH AMINO-TRIAZINE BASED MANNICH-COMPOUNDS | BOREALIS AG (AT) | 2018-03-07 | — | — | EP | disclosed |