Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 2/20 | 0.32 |
| ▸ | EZH2 | Q15910 | 2/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19984611 | 0.89 | GAA (0.46) | GAAPOLBTSHRATML3MBTL1 | |
| SCHEMBL20434798 | 0.88 | GAA (0.43) | GAATSHRHTTKMT2ALMNA | |
| SCHEMBL17931347 | 0.88 | GAA (0.42) | GAAPOLBTSHRRECQLALDH1A1 | |
| SCHEMBL7508238 | 0.86 | GAA (0.50) | GAAPOLBTSHRATML3MBTL1 | |
| SCHEMBL12972581 | 0.86 | GAA (0.50) | GAAPOLBTSHRATML3MBTL1 | |
| SCHEMBL19937113 | 0.86 | GAA (0.50) | GAAPOLBTSHRATML3MBTL1 | |
| SCHEMBL17643678 | 0.86 | GAA (0.41) | GAATSHR | |
| SCHEMBL7708866 | 0.85 | GAA (0.49) | GAAPOLBTSHRATML3MBTL1 | |
| SCHEMBL26785335 | 0.85 | GAA (0.49) | GAAPOLBTSHRATML3MBTL1 | |
| SCHEMBL12766974 | 0.85 | GAA (0.49) | GAAPOLBTSHRATML3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 66 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10913897-B2 | Compounds and liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2021-02-09 | — | — | US | disclosed |
| US-10907100-B2 | Compounds and liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2021-02-02 | — | — | US | disclosed |
| EP-3623451-B1 | COMPOUND | MERCK PATENT GMBH (DE) | 2021-01-20 | — | — | EP | disclosed |
| US-10723950-B2 | Liquid-crystalline mixtures | MERCK PATENT GMBH (DE) | 2020-07-28 | — | — | US | disclosed |
| EP-3400271-B1 | LIQUID-CRYSTALLINE MIXTURES | MERCK PATENT GMBH (DE) | 2020-07-22 | — | — | EP | disclosed |
| US-10626666-B2 | Device for regulating the passage of light | MERCK PATENT GMBH (DE) | 2020-04-21 | — | — | US | disclosed |
| EP-3623451-A1 | COMPOUND | Merck Patent GmbH (DE) | 2020-03-18 | — | — | EP | disclosed |
| WO-2019228939-A1 | COMPOUNDS AND LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2019-12-05 | — | — | WO | disclosed |
| WO-2019228938-A1 | COMPOUNDS AND LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2019-12-05 | — | — | WO | disclosed |
| US-10465114-B2 | Liquid-crystalline medium | MERCK PATENT GMBH (DE) | 2019-11-05 | — | — | US | disclosed |
| US-20130155338-A1 | SWITCH ELEMENT COMPRISING A LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2013-06-20 | — | — | US | disclosed |
| WO-2013060406-A1 | SWITCH ELEMENT COMPRISING A LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2013-05-02 | — | — | WO | disclosed |
| EP-2265691-B1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2012-08-29 | — | — | EP | disclosed |
| WO-2012100901-A1 | DEVICE CONTAINING A LIQUID CRYSTAL MEDIUM | MERCK PATENT GMBH (DE) | 2012-08-02 | — | — | WO | disclosed |
| WO-2012052100-A1 | SWITCH ELEMENT COMPRISING A LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2012-04-26 | — | — | WO | disclosed |
| WO-2012025182-A1 | SWITCH ELEMENT COMPRISING A LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2012-03-01 | — | — | WO | disclosed |
| EP-2423294-A1 | Switch element comprising a liquid-crystalline medium | Merck Patent GmbH (DE) | 2012-02-29 | — | — | EP | disclosed |
| WO-2011154077-A1 | SWITCH ELEMENT COMPRISING A LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2011-12-15 | — | — | WO | disclosed |
| US-20110101270-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-05-05 | — | — | US | disclosed |
| WO-2009129911-A1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH, (DE) | 2009-10-29 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10913897-B2 | Compounds and liquid-crystalline medium | VIM, NEFM, AQP1 | GAA 4024/4885POLB 264/4885TSHR 4296/4885 |
| US-10907100-B2 | Compounds and liquid-crystalline medium | VIM, NEFM, AQP1 | GAA 3823/4885POLB 318/4885TSHR 4035/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.