Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 5/20 | 0.32 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.32 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.32 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7473740 | 0.91 | KMT2A (0.45) | GAAKMT2AMEN1TSHRCYP2D6 | |
| SCHEMBL7481837 | 0.90 | KMT2A (0.46) | GAAKMT2AMEN1TSHRCYP2D6 | |
| SCHEMBL13386836 | 0.89 | KMT2A (0.44) | GAAKMT2AMEN1TSHRCYP2D6 | |
| SCHEMBL13474845 | 0.88 | KMT2A (0.43) | GAAKMT2AMEN1TSHRCYP2D6 | |
| SCHEMBL22064475 | 0.87 | KMT2A (0.42) | GAAKMT2AMEN1TSHRCYP2D6 | |
| SCHEMBL13474887 | 0.87 | KMT2A (0.44) | GAAKMT2AMEN1TSHRCYP2D6 | |
| SCHEMBL27957816 | 0.87 | KMT2A (0.44) | GAAKMT2AMEN1TSHRCYP2D6 | |
| SCHEMBL13474862 | 0.84 | KMT2A (0.45) | GAAKMT2AMEN1TSHRCYP2D6 | |
| SCHEMBL19884604 | 0.84 | KMT2A (0.41) | GAAKMT2AMEN1TSHRCYP2D6 | |
| SCHEMBL15672474 | 0.84 | TSHR (0.41) | GAAKMT2AMEN1TSHRCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2514800-B2 | Compounds and liquid crystalline medium | MERCK PATENT GMBH (DE) | 2018-03-07 | — | — | EP | disclosed |