SCHEMBL7473740

SCHEMBL7473740

CC(ON1C(C)(C)CC(OC(=O)CCCCCCCCC(=O)OC2CC(C)(C)N(OC(C)c3ccccc3)C(C)(C)C2)CC1(C)C)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.45
GAA P10253 2/20 0.45
MEN1 O00255 1/20 0.45
TSHR P16473 2/20 0.44
CYP2D6 P10635 1/20 0.40
LMNA P02545 2/20 0.39
FAAH O00519 5/20 0.35
NR1I2 O75469 1/20 0.35
ABCB11 O95342 1/20 0.35
ALDH1A1 P00352 1/20 0.35
ESR1 P03372 1/20 0.35
HSD17B10 Q99714 1/20 0.35
NAAA Q02083 2/20 0.35
S1PR5 Q9H228 2/20 0.34
S1PR1 P21453 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22064475 0.96 KMT2A (0.42) KMT2AGAAMEN1TSHRCYP2D6
SCHEMBL13474845 0.94 KMT2A (0.43) KMT2AGAAMEN1TSHRCYP2D6
SCHEMBL7481837 0.94 KMT2A (0.46) KMT2AGAAMEN1TSHRCYP2D6
SCHEMBL13386836 0.93 KMT2A (0.44) KMT2AGAAMEN1TSHRCYP2D6
SCHEMBL13474889 0.92 KMT2A (0.40) KMT2AGAAMEN1TSHRCYP2D6
SCHEMBL19937331 0.91 GAA (0.45) KMT2AGAAMEN1TSHRCYP2D6
SCHEMBL13474887 0.91 KMT2A (0.44) KMT2AGAAMEN1TSHRCYP2D6
SCHEMBL27957816 0.91 KMT2A (0.44) KMT2AGAAMEN1TSHRCYP2D6
SCHEMBL19884576 0.90 KMT2A (0.39) KMT2AGAAMEN1TSHRCYP2D6
SCHEMBL16866169 0.90 FAAH (0.40) KMT2AGAAMEN1TSHRCYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11312908-B2 Liquid crystal medium and liquid crystal display MERCK PATENT GMBH (DE) 2022-04-26 US disclosed
EP-3303518-B1 LIQUID-CRYSTAL MEDIUM MERCK PATENT GMBH (DE) 2020-06-10 EP disclosed
US-10465117-B2 Liquid-crystalline medium, method for the stabilization thereof, and liquid-crystal display MERCK PATENT GMBH (DE) 2019-11-05 US disclosed
US-20180163134-A1 LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2018-06-14 US disclosed
US-20180163136-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2018-06-14 US disclosed
US-20180163134-A1 LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2018-06-14 US disclosed
US-20180163136-A1 LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 2018-06-14 US disclosed
EP-3327102-A1 LIQUID CRYSTAL MEDIUM AND LIQUID CRYSTAL DISPLAY Merck Patent GmbH (DE) 2018-05-30 EP disclosed
EP-3327103-A1 LIQUID CRYSTAL MEDIUM, METHOD FOR THE STABILISATION THEREOF AND LIQUID CRYSTAL DISPLAY Merck Patent GmbH (DE) 2018-05-30 EP disclosed
US-9920248-B2 Compounds and liquid-crystalline medium MERCK PATENT GMBH (DE) 2018-03-20 US disclosed
US-20140111730-A1 Liquid-crystalline medium, method for the stabilization thereof, and liquid-crystal display MERCK PATENT GMBH (DE) 2014-04-24 US disclosed
EP-2722381-A2 Liquid crystal medium, method for the stabilisation thereof and liquid crystal display Merck Patent GmbH (DE) 2014-04-23 EP disclosed
US-20120268706-A1 COMPOUNDS AND LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2012-10-25 US disclosed
US-20120268706-A1 COMPOUNDS AND LIQUID-CRYSTALLINE MEDIUM MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2012-10-25 US disclosed
EP-0309402-B2 N-substituted hindered amine stabilizers CIBA SC HOLDING AG (CH) 2002-06-12 EP disclosed
EP-0309402-B1 N-substituted hindered amine stabilizers CIBA GEIGY AG (CH) 1995-01-11 EP disclosed
US-5204473-A O-substituted N-hydroxy hindered amine stabilizers CIBA-GEIGY CORPORATION (US) 1993-04-20 US disclosed
EP-0467844-A2 Prevention of oxidation in petrochemical extraction solvents CIBA-GEIGY AG (CH) 1992-01-22 EP disclosed
US-4921962-A REACTION OF AMINE WITH HYDROPEROXIDE CIBA-GEIGY CORPORATION (US) 1990-05-01 US disclosed
EP-0309402-A1 N-substituted hindered amine stabilizers CIBA-GEIGY AG (CH) 1989-03-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120268706-A1 COMPOUNDS AND LIQUID-CRYSTALLINE MEDIUM NEFM, VIM, FLNB KMT2A 4273/4885GAA 4098/4885MEN1 937/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.