Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 2/20 | 0.40 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.40 |
| ▸ | EGFR | P00533 | 4/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | NOX4 | Q9NPH5 | 2/20 | 0.33 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.33 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.33 |
| ▸ | CCR1 | P32246 | 2/20 | 0.32 |
| ▸ | CCR5 | P51681 | 2/20 | 0.32 |
| ▸ | CCR8 | P51685 | 2/20 | 0.32 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16685432 | 0.77 | LIMK1 (0.51) | EGFRLIMK1KDM4EMEN1KMT2A | |
| SCHEMBL29519419 | 0.77 | LIMK1 (0.51) | EGFRLIMK1KDM4EMEN1KMT2A | |
| SCHEMBL16919868 | 0.73 | PIM1 (0.38) | PIM1PIM2EGFRACHEBCHE | |
| SCHEMBL23606174 | 0.72 | CYP1A2 (0.35) | PIM1PIM2EGFRACHEKDM4E | |
| SCHEMBL16283905 | 0.72 | NPC1 (0.41) | PIM1PIM2EGFRACHELIMK1 | |
| SCHEMBL22627568 | 0.72 | EGFR (0.47) | PIM1PIM2EGFRLIMK1NOX4 | |
| SCHEMBL16785723 | 0.71 | PIM1 (0.42) | PIM1PIM2ACHEKDM4EALDH1A1 | |
| SCHEMBL22627523 | 0.70 | PIM1 (0.36) | PIM1PIM2EGFRACHEBCHE | |
| SCHEMBL25464256 | 0.70 | ROCK1 (0.36) | PIM1PIM2BCHEHTR1AADRA1D | |
| SCHEMBL19052486 | 0.69 | PIM1 (0.40) | PIM1PIM2KDM4EALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018043761-A1 | SPECIFICALLY SUBSTITUTED AZA-DIBENZOFURANS AND AZA-DIBENZOTHIOPHENES FOR ORGANIC ELECTRONIC DEVICES | IDEMITSU KOSAN CO.,LTD. (JP) | 2018-03-08 | — | — | WO | disclosed |