Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LIMK1 | P53667 | 2/20 | 0.51 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.51 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 5/20 | 0.42 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.41 |
| ▸ | KRAS | P01116 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | GPR3 | P46089 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16685432 | 1.00 | LIMK1 (0.51) | LIMK1CDK5CDK5R1EGFRHTR2C | |
| SCHEMBL22874230 | 0.81 | LIMK1 (0.54) | LIMK1CDK5CDK5R1EGFRHTR2C | |
| SCHEMBL16693325 | 0.79 | LIMK1 (0.51) | LIMK1CDK5CDK5R1EGFRHTR2C | |
| SCHEMBL13209223 | 0.79 | LIMK1 (0.51) | LIMK1CDK5CDK5R1EGFRHTR2C | |
| SCHEMBL19937109 | 0.79 | LIMK1 (0.51) | LIMK1CDK5CDK5R1EGFRHTR2C | |
| SCHEMBL19937337 | 0.77 | PIM1 (0.40) | LIMK1EGFRMEN1KMT2AKDM4E | |
| SCHEMBL24589835 | 0.76 | LIMK1 (0.49) | LIMK1CDK5CDK5R1EGFRHTR2C | |
| SCHEMBL18232948 | 0.76 | LIMK1 (0.49) | LIMK1CDK5CDK5R1EGFRHTR2C | |
| SCHEMBL23996427 | 0.76 | LIMK1 (0.49) | LIMK1CDK5CDK5R1EGFRHTR2C | |
| SCHEMBL7533955 | 0.75 | LIMK1 (0.51) | LIMK1CDK5CDK5R1EGFRHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109311904-B | Certain substituted benzofuro-and benzothienoquinolines for use in organic light emitting diodes | 出光兴产株式会社 | 2022-03-29 | — | — | CN | disclosed |