Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15672481 | 0.84 | GAA (0.41) | GAAL3MBTL1HTT | |
| SCHEMBL16518712 | 0.78 | GAA (0.36) | GAAL3MBTL1HTT | |
| SCHEMBL4409167 | 0.78 | GAA (0.36) | GAAL3MBTL1HTT | |
| SCHEMBL15672512 | 0.77 | GAA (0.39) | GAAKDM4EL3MBTL1HTT | |
| SCHEMBL16790813 | 0.77 | GAA (0.39) | GAAL3MBTL1HTT | |
| SCHEMBL19720362 | 0.75 | GAA (0.38) | GAAL3MBTL1HTT | |
| SCHEMBL987059 | 0.75 | GAA (0.38) | GAAL3MBTL1HTT | |
| SCHEMBL13554331 | 0.75 | GAA (0.34) | GAAL3MBTL1HTTKMT2A | |
| SCHEMBL16869851 | 0.75 | GAA (0.34) | GAAL3MBTL1HTT | |
| SCHEMBL19735148 | 0.73 | SGPL1 (0.33) | GAAL3MBTL1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2514800-B2 | Compounds and liquid crystalline medium | MERCK PATENT GMBH (DE) | 2018-03-07 | — | — | EP | disclosed |