Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | CHRNA7 | P36544 | 5/20 | 0.47 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.46 |
| ▸ | HTR3B | O95264 | 1/20 | 0.46 |
| ▸ | HTR3A | P46098 | 1/20 | 0.46 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.46 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.41 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19937388 | 0.85 | CYP2D6 (0.41) | TSHRGAAKMT2APOLBCYP2D6 | |
| SCHEMBL9410304 | 0.85 | TSHR (0.54) | TSHRGAAKMT2ACHRNA7HTR3E | |
| SCHEMBL19937281 | 0.83 | CYP2D6 (0.40) | TSHRGAAKMT2AMEN1POLB | |
| SCHEMBL7857242 | 0.83 | TSHR (0.67) | TSHRGAAKMT2ACHRNA7HTR3E | |
| SCHEMBL9410280 | 0.83 | TSHR (0.57) | TSHRGAAKMT2ACHRNA7HTR3E | |
| SCHEMBL19937404 | 0.82 | TSHR (0.39) | TSHRGAAKMT2AMEN1CYP2D6 | |
| SCHEMBL9065750 | 0.82 | TSHR (0.65) | TSHRGAAKMT2ACHRNA7HTR3E | |
| SCHEMBL9410338 | 0.81 | TSHR (0.55) | TSHRGAAKMT2ACHRNA7HTR3E | |
| SCHEMBL11175662 | 0.81 | TSHR (0.55) | TSHRGAAKMT2ACHRNA7HTR3E | |
| SCHEMBL11451796 | 0.80 | TSHR (0.62) | TSHRGAAKMT2ACHRNA7HTR3E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2514800-B2 | Compounds and liquid crystalline medium | MERCK PATENT GMBH (DE) | 2018-03-07 | — | — | EP | disclosed |