Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.57 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | CHRNA7 | P36544 | 5/20 | 0.46 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.46 |
| ▸ | HTR3B | O95264 | 1/20 | 0.46 |
| ▸ | HTR3A | P46098 | 1/20 | 0.46 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.46 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.41 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.41 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.40 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11175662 | 0.88 | TSHR (0.55) | TSHRGAAKMT2ACHRNA7HTR3E | |
| SCHEMBL9410338 | 0.88 | TSHR (0.55) | TSHRGAAKMT2ACHRNA7HTR3E | |
| SCHEMBL9359743 | 0.86 | TSHR (0.53) | TSHRGAAKMT2A | |
| SCHEMBL9410300 | 0.85 | TSHR (0.52) | TSHRGAAKMT2ACHRNA7HTR3E | |
| SCHEMBL11181676 | 0.83 | TSHR (0.50) | TSHRGAAKMT2ACHRNA7HTR3E | |
| SCHEMBL7857242 | 0.83 | TSHR (0.67) | TSHRGAAKMT2ACHRNA7HTR3E | |
| SCHEMBL19937397 | 0.83 | TSHR (0.57) | TSHRGAAKMT2ACHRNA7HTR3E | |
| SCHEMBL9410270 | 0.82 | KMT2A (0.52) | TSHRGAAKMT2ACHRNA7HTR3E | |
| SCHEMBL9410283 | 0.82 | TSHR (0.49) | TSHRGAAKMT2ACHRNA7HTR3E | |
| SCHEMBL9410281 | 0.82 | KMT2A (0.57) | TSHRGAAKMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1091128-A | Piperidine derivative | SANKYO CO (JP) | 1994-08-24 | — | — | CN | disclosed |
| EP-0583971-A1 | Piperidine derivatives | SANKYO COMPANY LIMITED (JP) | 1994-02-23 | — | — | EP | disclosed |