Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.31 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.31 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23794079 | 0.96 | — | — | |
| SCHEMBL8618471 | 0.73 | GRIN1 (0.33) | GRIN1GRIN2ASLC6A4GRIN2DGRIN3B | |
| SCHEMBL8677429 | 0.70 | — | — | |
| SCHEMBL8623989 | 0.70 | — | — | |
| SCHEMBL7757227 | 0.70 | GRIN1 (0.31) | GRIN1GRIN2ASLC6A4GRIN2DGRIN3B | |
| SCHEMBL2076716 | 0.69 | — | — | |
| SCHEMBL4355834 | 0.69 | — | — | |
| SCHEMBL19411896 | 0.68 | POLB (0.39) | POLBGRIN1GRIN2ASLC6A4GRIN2D | |
| SCHEMBL19411897 | 0.68 | POLB (0.39) | POLBGRIN1GRIN2ASLC6A4GRIN2D | |
| SCHEMBL12857078 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230399309-A1 | DEUTERATED HPK1 KINASE INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | Guangzhou Yufan Nantu Biotechnologies Co., Ltd (CN) | 2023-12-14 | — | — | US | disclosed |
| US-20210040119-A1 | PROCESS FOR THE PREPARATION OF A SUBSTITUTED IMIDAZOTHIAZOLONE COMPOUND | DSM IP ASSETS BV (NL) | 2021-02-11 | — | — | US | disclosed |
| US-20180065990-A1 | PROCESS FOR THE PREPARATION OF A SUBSTITUTED IMIDAZOTHIAZOLONE COMPOUND | DSM IP ASSETS B.V. (NL) | 2018-03-08 | — | — | US | disclosed |
| US-20180065990-A1 | PROCESS FOR THE PREPARATION OF A SUBSTITUTED IMIDAZOTHIAZOLONE COMPOUND | DSM IP ASSETS B.V. (NL) | 2018-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230399309-A1 | DEUTERATED HPK1 KINASE INHIBITOR, AND PREPARATION METHOD THEREFOR AND USE THEREOF | WEE1, WEE2, VRK1 | POLB 3863/4885GRIN1 1836/4885GRIN2A 4386/4885 |
| US-20210040119-A1 | PROCESS FOR THE PREPARATION OF A SUBSTITUTED IMIDAZOTHIAZOLONE COMPOUND | ABL1, KRAS, FLI1 | POLB 3020/4885GRIN1 2200/4885GRIN2A 1712/4885 |
| US-20180065990-A1 | PROCESS FOR THE PREPARATION OF A SUBSTITUTED IMIDAZOTHIAZOLONE COMPOUND | ABL1, KRAS, FLI1 | POLB 3045/4885GRIN1 2253/4885GRIN2A 1785/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.