Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN1 | Q05586 | 3/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.31 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 2/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 2/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.31 |
| ▸ | GRIN2C | Q14957 | 2/20 | 0.31 |
| ▸ | GRIN3A | Q8TCU5 | 2/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.31 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8618471 | 0.73 | GRIN1 (0.33) | GRIN1GRIN2ASLC6A4GRIN2DGRIN3B | |
| SCHEMBL19938124 | 0.70 | POLB (0.31) | GRIN1GRIN2ASLC6A4GRIN2DGRIN3B | |
| SCHEMBL12478883 | 0.69 | — | — | |
| SCHEMBL7022608 | 0.67 | TRIM24 (0.36) | GRIN1GRIN2ASLC6A4GRIN2DGRIN3B | |
| SCHEMBL2076716 | 0.65 | — | — | |
| SCHEMBL8623989 | 0.65 | — | — | |
| SCHEMBL2535219 | 0.65 | POLB (0.31) | GRIN1GRIN2ASLC6A4GRIN2DGRIN3B | |
| SCHEMBL104646 | 0.64 | — | — | |
| SCHEMBL8153538 | 0.64 | HTT (0.33) | GRIN1GRIN2ASLC6A4GRIN2DGRIN3B | |
| SCHEMBL25182793 | 0.64 | POLB (0.30) | GRIN1GRIN2ASLC6A4GRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0882007-B1 | PREPARATION OF ALPHA-FLUOROKETONES | F2 CHEMICALS LTD (GB) | 2001-03-14 | — | — | EP | disclosed |
| US-6031139-A | Preparation of α-fluoroketones | F2 CHEMICALS LIMITED (GB) | 2000-02-29 | — | — | US | disclosed |
| EP-0882007-A1 | PREPARATION OF ALPHA-FLUOROKETONES | F2 Chemicals Limited (GB) | 1998-12-09 | — | — | EP | disclosed |
| WO-1997046508-A1 | PREPARATION OF ALPHA-FLUOROKETONES | F2 CHEMICALS LIMITED (GB) | 1997-12-11 | — | — | WO | disclosed |