Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19938607 | 0.89 | MAPT (0.36) | MAPTSMN1; SMN2NPSR1 | |
| SCHEMBL19939036 | 0.87 | — | — | |
| SCHEMBL19939033 | 0.83 | — | — | |
| SCHEMBL19939016 | 0.83 | P2RX4 (0.31) | — | |
| SCHEMBL19938321 | 0.83 | P2RX4 (0.32) | — | |
| SCHEMBL19938553 | 0.82 | MAPT (0.32) | MAPTSMN1; SMN2NPSR1 | |
| SCHEMBL24027100 | 0.81 | P2RX4 (0.36) | MAPTSMN1; SMN2NPSR1 | |
| SCHEMBL19939002 | 0.80 | — | — | |
| SCHEMBL19939037 | 0.80 | MAPT (0.30) | MAPTSMN1; SMN2NPSR1 | |
| SCHEMBL19939050 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11653565-B2 | Polycyclic aromatic compound | KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) | 2023-05-16 | — | — | US | disclosed |
| US-11653565-B2 | Polycyclic aromatic compound | KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) | 2023-05-16 | — | — | US | disclosed |
| US-20200220083-A1 | POLYCYCLIC AROMATIC COMPOUND | KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) | 2020-07-09 | — | — | US | disclosed |
| US-10686141-B2 | Polycyclic aromatic compound | KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) | 2020-06-16 | — | — | US | disclosed |
| US-20180069182-A1 | POLYCYCLIC AROMATIC COMPOUND | KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) | 2018-03-08 | — | — | US | disclosed |
| US-20180069182-A1 | POLYCYCLIC AROMATIC COMPOUND | KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) | 2018-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11653565-B2 | Polycyclic aromatic compound | ETV6, EBPL, EML4 | MAPT 1228/4885SMN1; SMN2 3481/4885NPSR1 3158/4885 |
| US-10686141-B2 | Polycyclic aromatic compound | ETV6, EBPL, EML4 | MAPT 1228/4885SMN1; SMN2 3481/4885NPSR1 3158/4885 |
| US-20180069182-A1 | POLYCYCLIC AROMATIC COMPOUND | ETV6, EBPL, EML4 | MAPT 1228/4885SMN1; SMN2 3481/4885NPSR1 3158/4885 |
| US-20200220083-A1 | POLYCYCLIC AROMATIC COMPOUND | ETV6, EBPL, EML4 | MAPT 1228/4885SMN1; SMN2 3481/4885NPSR1 3158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.