Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX4 | Q99571 | 4/20 | 0.40 |
| ▸ | ELANE | P08246 | 2/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | CTSG | P08311 | 1/20 | 0.38 |
| ▸ | CMA1 | P23946 | 1/20 | 0.38 |
| ▸ | CTRC | Q99895 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19938523 | 0.86 | P2RX4 (0.37) | P2RX4MGLLALDH1A1HPGDGAA | |
| SCHEMBL19938532 | 0.84 | PDE6D (0.40) | P2RX4MGLLALDH1A1 | |
| SCHEMBL19939108 | 0.83 | P2RX4 (0.34) | P2RX4 | |
| SCHEMBL19938610 | 0.83 | P2RX4 (0.37) | P2RX4MGLLALDH1A1HPGDGAA | |
| SCHEMBL19938478 | 0.81 | PDE6D (0.40) | P2RX4MGLLALDH1A1 | |
| SCHEMBL19938643 | 0.79 | ELANE (0.38) | P2RX4ELANEF2CTSGCMA1 | |
| SCHEMBL19938665 | 0.78 | P2RX4 (0.30) | P2RX4 | |
| SCHEMBL19939076 | 0.77 | GAA (0.37) | P2RX4MGLLALDH1A1MAPTHPGD | |
| SCHEMBL19939086 | 0.77 | GAA (0.33) | P2RX4MGLLALDH1A1HPGDGAA | |
| SCHEMBL10001963 | 0.77 | P2RX4 (0.53) | P2RX4ELANEF2CTSGCMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11653565-B2 | Polycyclic aromatic compound | KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) | 2023-05-16 | — | — | US | disclosed |
| US-11653565-B2 | Polycyclic aromatic compound | KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) | 2023-05-16 | — | — | US | disclosed |
| US-20200220083-A1 | POLYCYCLIC AROMATIC COMPOUND | KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) | 2020-07-09 | — | — | US | disclosed |
| US-10686141-B2 | Polycyclic aromatic compound | KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) | 2020-06-16 | — | — | US | disclosed |
| US-20180069182-A1 | POLYCYCLIC AROMATIC COMPOUND | KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) | 2018-03-08 | — | — | US | disclosed |
| US-20180069182-A1 | POLYCYCLIC AROMATIC COMPOUND | KWANSEI GAKUIN EDUCATIONAL FOUNDATION (JP) | 2018-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11653565-B2 | Polycyclic aromatic compound | ETV6, EBPL, EML4 | P2RX4 1752/4885ELANE 187/4885F2 3061/4885 |
| US-10686141-B2 | Polycyclic aromatic compound | ETV6, EBPL, EML4 | P2RX4 1752/4885ELANE 187/4885F2 3061/4885 |
| US-20180069182-A1 | POLYCYCLIC AROMATIC COMPOUND | ETV6, EBPL, EML4 | P2RX4 1752/4885ELANE 187/4885F2 3061/4885 |
| US-20200220083-A1 | POLYCYCLIC AROMATIC COMPOUND | ETV6, EBPL, EML4 | P2RX4 1752/4885ELANE 187/4885F2 3061/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.