Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.38 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 2/20 | 0.35 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CDK1 | P06493 | 1/20 | 0.35 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13776183 | 0.84 | LPAR1 (0.45) | HSP90AA1HSP90AB1KDM4EALDH1A1GAA | |
| SCHEMBL13775974 | 0.82 | HSP90AA1 (0.40) | HSP90AA1HSP90AB1ELANECTRB1ALDH1A1 | |
| SCHEMBL4119701 | 0.81 | LPAR1 (0.45) | HSP90AA1HSP90AB1KDM4EALDH1A1GAA | |
| SCHEMBL30478220 | 0.81 | HSP90AA1 (0.38) | HSP90AA1HSP90AB1ELANECTRB1PTGER1 | |
| SCHEMBL8254664 | 0.81 | AAK1 (0.39) | HSP90AA1HSP90AB1GAAAAK1MEN1 | |
| SCHEMBL4119464 | 0.80 | LPAR1 (0.51) | HSP90AA1HSP90AB1KDM4EALDH1A1GAA | |
| SCHEMBL13776189 | 0.80 | HSP90AA1 (0.44) | HSP90AA1HSP90AB1LPAR1IDO1MEN1 | |
| SCHEMBL4122839 | 0.78 | LMNA (0.46) | HSP90AA1HSP90AB1KDM4EALDH1A1GAA | |
| SCHEMBL13776193 | 0.78 | HSP90AA1 (0.41) | HSP90AA1HSP90AB1LPAR1IDO1 | |
| SCHEMBL13776424 | 0.78 | HSP90AA1 (0.43) | HSP90AA1HSP90AB1ALDH1A1HPGDLPAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230263805-A1 | DEUTERATED ANALOGS OF ETIFOXINE, THEIR DERIVATIVES AND USES THEREOF | GABA THERAPEUTICS INC (US) | 2023-08-24 | — | — | US | disclosed |
| US-11672805-B2 | Deuterated analogs of etifoxine, their derivatives and uses thereof | GABA THERAPEUTICS INC. (US) | 2023-06-13 | — | — | US | disclosed |
| US-20180064717-A1 | DEUTERATED ANALONGS OF ETIFOXINE, THEIR DERIVATIVES AND USES THEREOF | GABA THERAPEUTICS INC. | 2018-03-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180064717-A1 | DEUTERATED ANALONGS OF ETIFOXINE, THEIR DERIVATIVES AND USES THEREOF | CYP2D6, CYP2S1, CYP3A43 | HSP90AA1 3131/4885HSP90AB1 3068/4885ELANE 1908/4885 |
| US-11672805-B2 | Deuterated analogs of etifoxine, their derivatives and uses thereof | CYP2F1, CYP3A5, CYP4F3 | HSP90AA1 2701/4885HSP90AB1 2312/4885ELANE 2711/4885 |
| US-20230263805-A1 | DEUTERATED ANALOGS OF ETIFOXINE, THEIR DERIVATIVES AND USES THEREOF | CYP2F1, CYP3A5, CYP4F3 | HSP90AA1 2701/4885HSP90AB1 2312/4885ELANE 2711/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.