Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.51 |
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | TP53 | P04637 | 3/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19939686 | 1.00 | MAPT (0.51) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL19939685 | 1.00 | MAPT (0.51) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL19937940 | 1.00 | MAPT (0.51) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL19937945 | 0.92 | MAPT (0.48) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL19937943 | 0.92 | MAPT (0.48) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL19937944 | 0.92 | MAPT (0.48) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL19937946 | 0.92 | MAPT (0.48) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL19937942 | 0.91 | MAPT (0.49) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL19937919 | 0.88 | MAPT (0.53) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL26440959 | 0.86 | MAPT (0.57) | MAPTLMNAMEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018045104-A1 | ANTI-PARASITIC COMPOUNDS | OHIO STATE INNOVATION FOUNDATION (US) | 2018-03-08 | — | — | WO | disclosed |
| WO-2018045106-A1 | ANTI-FUNGAL TREATMENT | OHIO STATE INNOVATION FOUNDATION (US) | 2018-03-08 | — | — | WO | disclosed |