Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.57 |
| ▸ | MEN1 | O00255 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | TP53 | P04637 | 3/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.55 |
| ▸ | RELA | Q04206 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26132002 | 0.87 | ALDH1A1 (0.50) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL26434280 | 0.87 | LMNA (0.57) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL19939702 | 0.86 | MAPT (0.51) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL26434206 | 0.86 | MAPK1 (0.50) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL19939686 | 0.86 | MAPT (0.51) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL19939685 | 0.86 | MAPT (0.51) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL19937940 | 0.86 | MAPT (0.51) | MAPTLMNAMEN1KMT2AKDM4E | |
| SCHEMBL26133377 | 0.83 | LTB4R (0.46) | MAPTLMNAKDM4ERAB9ATP53 | |
| SCHEMBL14599576 | 0.82 | PPARA (0.52) | KMT2ASMN1; SMN2NPC1RAB9A | |
| SCHEMBL26132334 | 0.81 | NOS1 (0.58) | LMNAKDM4ESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023069613-A1 | ARYLIMIDAMIDES FOR USE IN TREATMENT OF CANCERS | OHIO STATE INNOVATION FOUNDATION (US) | 2023-04-27 | — | — | WO | disclosed |