SCHEMBL1994009

SCHEMBL1994009

CCCCO[Hf](Cl)(OCCCC)OCCCC

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 1/20 0.41
ADRB1 P08588 1/20 0.41
ADRB3 P13945 1/20 0.41
TSHR P16473 7/20 0.36
CYP3A4 P08684 2/20 0.36
ALDH1A1 P00352 3/20 0.35
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
LMNA P02545 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
ATM Q13315 1/20 0.32
THRB P10828 1/20 0.32
DNM1 Q05193 3/20 0.30
MEN1 O00255 1/20 0.30
KMT2A Q03164 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7596598 0.92 TSHR (0.37) TSHRALDH1A1CA1CA2THRB
SCHEMBL7114977 0.82 ADRB2 (0.41) ADRB2ADRB1ADRB3TSHRCYP3A4
SCHEMBL7592590 0.81
SCHEMBL468634 0.75 ADRB2 (0.45) ADRB2ADRB1ADRB3TSHRCYP3A4
SCHEMBL7590862 0.74 TSHR (0.37) TSHRALDH1A1CA1CA2THRB
SCHEMBL7591842 0.74 LPAR3 (0.39) TSHRALDH1A1CA1CA2THRB
Lithium Ion SCHEMBL8690674 0.73
SCHEMBL7597810 0.71 ADRB2 (0.41) ADRB2ADRB1ADRB3TSHRCYP3A4
SCHEMBL7593315 0.71
SCHEMBL7591750 0.71 ADRB2 (0.41) ADRB2ADRB1ADRB3TSHRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 65 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2495261-B1 SUPPORTED NON-METALLOCENE CATALYST, MANUFACTURING METHOD AND APPLICATION THEREOF CHINA PETROLEUM & CHEM CORP (CN) 2020-08-26 EP disclosed
EP-2500365-B1 SUPPORTED NON-METALLOCENE CATALYST AND PREPARATION METHOD AND USES THEREOF CHINA PETROLEUM & CHEM CORP (CN) 2020-05-06 EP disclosed
EP-2500364-B1 SUPPORTED NON-METALLOCENE CATALYST PREPARATION METHOD AND APPLICATION THEREOF CHINA PETROLEUM & CHEM CORP (CN) 2020-03-04 EP disclosed
EP-2202246-B1 NON-METALLOCENE CATALYST SUPPORTED ON MAGNESIUM COMPOUND AND ITS PREPARATION METHOD SINOPEC YANGZI PETROCHEMICAL (CN) 2016-06-15 EP disclosed
US-9334339-B2 Supported nonmetallocene catalysts, preparation and use thereof CHINA PETROLEUM & CHEMICAL CORPORATION (CN) 2016-05-10 US disclosed
US-8981023-B2 Supported nonmetallocene catalyst, preparation and use thereof CHINA PETROLEUM & CHEMICAL CORP. (CN) 2015-03-17 US disclosed
US-8957169-B2 Supported nonmetallocene catalyst, preparation and use thereof CHINA PETROLEUM & CHEMICAL CORP. (CN) 2015-02-17 US disclosed
US-8952113-B2 Supported nonmetallocene catalyst, preparation and use thereof CHINA PETROLEUM & CHEMICAL CORP. (CN) 2015-02-10 US disclosed
US-8952112-B2 Supported nonmetallocene catalyst, preparation and use thereof CHINA PETROLEUM & CHEMICAL CORP. (CN) 2015-02-10 US disclosed
US-20140364576-A1 SUPPORTED NONMETALLOCENE CATALYSTS, PREPARATION AND USE THEREOF SINOPEC YANGZI PETROCHEMICAL COMPANY LTD. (CN) 2014-12-11 US disclosed
US-5387567-A An additional polymerization catalysts consisting of a metal compounds selected from zirconium, titanium, hafnium and organosilane compound; molecular weight controller for broad molecular weight distribution NIPPON OIL CO., LTD. (JP) 1995-02-07 US disclosed
US-5331071-A Transition metal and alumoxane components NIPPON OIL CO., LTD. (JP) 1994-07-19 US disclosed
EP-0587440-A2 Catalyst component for the polymerisation of olefins and process for preparing olefin polymers using same NIPPON OIL COMPANY, LIMITED (JP) 1994-03-16 EP disclosed
EP-0570931-A2 Styrenic polymer, process for producing same and multi-layer material comprising same IDEMITSU KOSAN COMPANY LIMITED (JP) 1993-11-24 EP disclosed
EP-0570932-A2 Styrenic block copolymer and process for producing same IDEMITSU KOSAN COMPANY LIMITED (JP) 1993-11-24 EP disclosed
EP-0569249-A2 Ethylene/alpha-olefin copolymers NIPPON OIL COMPANY, LIMITED (JP) 1993-11-10 EP disclosed
US-5250629-A Graft polymerization of styrene and ethylenically unsaturated monomer using transition metal catalysts, organoaluminum compounds; films, packaging, automobile parts IDEMITSU KOSAN CO., LTD. (JP) 1993-10-05 US disclosed
EP-0520811-A2 Catalyst components for polymerization of olefins NIPPON OIL CO. LTD. (JP) 1992-12-30 EP disclosed
EP-0511407-A1 STYRENIC COPOLYMER AND PRODUCTION THEREOF IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-11-04 EP disclosed
EP-0490269-A1 Graft copolymer and process for producing the same IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-06-17 EP disclosed