Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | APEX1 | P27695 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.48 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.48 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.40 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | HRH2 | P25021 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19940074 | 1.00 | POLB (0.55) | POLBAPEX1HTTTDP1PSMB1 | |
| SCHEMBL10886240 | 0.85 | ADORA3 (0.44) | POLBAPEX1HTTTDP1PSMB1 | |
| SCHEMBL14173065 | 0.81 | POLB (0.45) | POLBAPEX1HTTTDP1PSMB1 | |
| SCHEMBL21422397 | 0.81 | CA1 (0.44) | POLBAPEX1HTTTDP1MEN1 | |
| SCHEMBL26007788 | 0.80 | POLB (0.41) | POLBAPEX1HTTTDP1PSMB1 | |
| SCHEMBL13588352 | 0.80 | ADORA3 (0.40) | POLBAPEX1HTTTDP1PSMB1 | |
| SCHEMBL14727679 | 0.79 | HTT (0.50) | POLBAPEX1HTTTDP1MEN1 | |
| SCHEMBL2703811 | 0.79 | KMT2A (0.49) | POLBHTTPSMB1PSMB5PSMB2 | |
| SCHEMBL14173280 | 0.79 | HTT (0.68) | POLBAPEX1HTTTDP1TSHR | |
| SCHEMBL14173281 | 0.79 | HTT (0.68) | POLBAPEX1HTTTDP1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018043746-A1 | PHOTOSENSITIVE RESIN COMPOSITION FOR FORMING ORGANIC ELECTROLUMINESCENT ELEMENT PARTITION WALL, PARTITION WALL, ORGANIC ELECTROLUMINESCENT ELEMENT, IMAGE DISPLAY DEVICE AND LIGHTING | 三菱ケミカル株式会社 | 2018-03-08 | — | — | WO | disclosed |