Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PROKR1 | Q8TCW9 | 17/20 | 0.62 |
| ▸ | FPR2 | P25090 | 16/20 | 0.62 |
| ▸ | CCR3 | P51677 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19941063 | 0.78 | FPR2 (0.61) | PROKR1FPR2CCR3 | |
| SCHEMBL15548934 | 0.77 | PROKR1 (1.00) | PROKR1FPR2 | |
| SCHEMBL19941111 | 0.73 | FPR2 (0.61) | PROKR1FPR2 | |
| SCHEMBL19941205 | 0.72 | FPR2 (0.62) | PROKR1FPR2 | |
| SCHEMBL19941243 | 0.71 | FPR2 (0.60) | PROKR1FPR2 | |
| SCHEMBL19941046 | 0.69 | FPR2 (0.60) | PROKR1FPR2 | |
| SCHEMBL14935031 | 0.69 | FPR2 (0.50) | PROKR1FPR2CCR3HTR2AKMT2A | |
| SCHEMBL19941256 | 0.68 | FPR2 (0.57) | PROKR1FPR2 | |
| SCHEMBL19941134 | 0.68 | FPR2 (0.60) | PROKR1FPR2 | |
| SCHEMBL19941281 | 0.68 | FPR2 (0.61) | PROKR1FPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2855449-B1 | SULFONYL PIPERIDINE DERIVATIVES AND THEIR USE FOR TREATING PROKINETICIN MEDIATED DISEASES | TAKEDA PHARMACEUTICALS CO (JP) | 2018-03-07 | — | — | EP | disclosed |