⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21266702 | 0.83 | — | — | |
| SCHEMBL19942357 | 0.64 | KDM4E (0.30) | — | |
| SCHEMBL19942422 | 0.64 | DPP4 (0.31) | — | |
| SCHEMBL19942190 | 0.63 | ALDH1A1 (0.39) | — | |
| SCHEMBL12588784 | 0.60 | — | — | |
| SCHEMBL19939393 | 0.58 | RXFP1 (0.39) | — | |
| SCHEMBL21509288 | 0.56 | — | — | |
| SCHEMBL24198469 | 0.55 | PIK3CG (0.40) | — | |
| SCHEMBL19942418 | 0.54 | ALDH1A1 (0.39) | — | |
| SCHEMBL8311390 | 0.54 | HAVCR2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11731977-B2 | SGC stimulators | CYCLERION THERAPEUTICS, INC. (US) | 2023-08-22 | — | — | US | disclosed |
| US-20220009937-A1 | sGC STIMULATORS | TISENTO THERAPEUTICS INC. | 2022-01-13 | — | — | US | disclosed |
| US-20210087198-A1 | sGC STIMULATORS | TISENTO THERAPEUTICS INC. | 2021-03-25 | — | — | US | disclosed |
| US-10472363-B2 | SGC stimulators | CYCLERION THERAPEUTICS, INC. (US) | 2019-11-12 | — | — | US | disclosed |
| US-20180065971-A1 | sGC STIMULATORS | TISENTO THERAPEUTICS INC. | 2018-03-08 | — | — | US | disclosed |