Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 8/20 | 0.34 |
| ▸ | POLB | P06746 | 4/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.34 |
| ▸ | HPGD | P15428 | 5/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.34 |
| ▸ | RAB9A | P51151 | 5/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.34 |
| ▸ | NPC1 | O15118 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.34 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.34 |
| ▸ | RELA | Q04206 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 7/20 | 0.34 |
| ▸ | CASP3 | P42574 | 3/20 | 0.34 |
| ▸ | SENP7 | Q9BQF6 | 3/20 | 0.34 |
| ▸ | SENP6 | Q9GZR1 | 3/20 | 0.34 |
| ▸ | SENP8 | Q96LD8 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29431610 | 0.89 | UTRN (0.38) | TP53SMN1; SMN2KDM4EHPGDALDH1A1 | |
| SCHEMBL15846613 | 0.89 | UTRN (0.38) | TP53SMN1; SMN2KDM4EHPGDALDH1A1 | |
| SCHEMBL25766299 | 0.87 | TP53 (0.31) | TP53POLBRXFP1SMN1; SMN2KDM4E | |
| SCHEMBL19302014 | 0.85 | HDAC3 (0.32) | UTRN | |
| SCHEMBL20867331 | 0.85 | UTRN (0.32) | TP53SMN1; SMN2KDM4EHPGDALDH1A1 | |
| SCHEMBL30970967 | 0.85 | HDAC3 (0.32) | UTRN | |
| SCHEMBL21051281 | 0.84 | UTRN (0.33) | UTRN | |
| SCHEMBL29603696 | 0.84 | UTRN (0.33) | TP53POLBSMN1; SMN2KDM4EHPGD | |
| SCHEMBL20489570 | 0.84 | UTRN (0.33) | TP53POLBSMN1; SMN2KDM4EHPGD | |
| SCHEMBL29431601 | 0.84 | ALDH1A1 (0.36) | TP53POLBRXFP1SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3508485-B1 | HYDRAZONYL GROUP CONTAINING-CONDENSED HETEROCYCLIC COMPOUND OR SALT THEREOF, AGRICULTURAL AND HORTICULTURAL INSECTICIDE COMPRISING THE COMPOUND, AND METHOD FOR USING THE INSECTICIDE | NIHON NOHYAKU CO LTD (JP) | 2021-02-24 | — | — | EP | disclosed |
| EP-3508485-A1 | FUSED HETEROCYCLIC COMPOUND HAVING HYDRAZONYL GROUP OR SALTS THEREOF, PESTICIDE FOR AGRICULTURAL AND HORTICULTURAL USE CONTAINING SAID COMPOUND, AND METHOD FOR USING SAME | Nihon Nohyaku Co., Ltd. (JP) | 2019-07-10 | — | — | EP | disclosed |
| WO-2018043675-A1 | FUSED HETEROCYCLIC COMPOUND HAVING HYDRAZONYL GROUP OR SALTS THEREOF, PESTICIDE FOR AGRICULTURAL AND HORTICULTURAL USE CONTAINING SAID COMPOUND, AND METHOD FOR USING SAME | 日本農薬株式会社 | 2018-03-08 | — | — | WO | disclosed |